Biopolymers are a leading class of functional material suitable for high-value applications and are of great interest to researchers and professionals across various disciplines. Interdisciplinary research is important to understand the basic and applied aspects of biopolymers to address several complex problems associated with good health and well-being. To reduce the environmental impact and dependence on fossil fuels, a lot of effort has gone into replacing synthetic polymers with biodegradable materials, especially those derived from natural resources. In this regard, many types of natural or biopolymers have been developed to meet the needs of ever-expanding applications. These biopolymers are currently used in food applications and are expanding their use in the pharmaceutical and medical industries due to their unique properties. This review focuses on the various uses of biopolymers in the food and medical industry and provides a future outlook for the biopolymer industry.
The world of sensors is diverse and is advancing at a rapid pace due to the fact of its high demand and constant technological improvements. Electrochemical sensors provide a low-cost and convenient solution for the detection of variable analytes and are widely utilized in agriculture, food, and oil industries as well as in environmental and biomedical applications. The popularity of electrochemical sensing stems from two main advantages: the variability of the reporting signals, such as the voltage, current, overall power output, or electrochemical impedance, and the low theoretical detection limits that originate from the differences in the Faradaic and nonFaradaic currents. This review article attempts to cover the latest advances and applications of electrochemical sensors in different industries. The role of nanomaterials in electrochemical sensor research and advancements is also examined. We believe the information presented here will encourage further efforts on the understanding and progress of electrochemical sensors.
The development of new fluorescent molecules for the
recognition
of specific G-quadruplex DNA structures has attracted wide attention
due to their diverse roles in drug design, sensing, and cellular probing.
In this work, we report the discovery of a red-emissive styryl quinolinium-based
molecular rotor (compound 1), which recognizes human
telomeric G-quadruplex with a distinct preference over DNA duplexes.
Optical spectroscopy (UV–vis and circular dichroism)-based
experiments indicated discernible interaction of compound 1 with the human telomeric DNA G-quadruplex with features of stacking
interactions. Fluorescence-based Job's plot revealed a 1:1 binding
stoichiometry between compound 1 and the human telomeric
DNA G-quadruplex, and subsequent titration experiments showed micromolar
affinities (K
a = 0.51 × 106 M–1). Molecular docking experiments showed interactions
of compound 1 in the grooves of the quadruplex. Finally,
we provide the application of compound 1 as a reporter
molecule in the fluorescence displacement experiments, which showed
its ability to act as a fluorescent probe compatible with ligands
having aromatic cores.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.