Acute mesenteric ischemia in COVID-19: Case report and current understanding

Chandrakar, Saurabh; Sangadala, Priyanka; Gupta, Megha; A, Deepak Kumar; Agarwal, Ankit

doi:10.5339/qmj.2022.11

Cited by 3 publications

(9 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the studies that cited the gastrointestinal clinical manifestations, the most frequent was abdominal pain with or without other complaints ( Table 1 ), being characterized as intense 7 , 8 , 20 , 24 , 25 , 30 , 31 , 38 , 39 , 41 , 43 , 44 , 51 , 62 , of sudden onset 8 , 31 , 35 , 36 , 38 - 40 , 47 , 58 , 59 , in cramps and without clear triggering factor 34 , 49 , 51 , of diffuse location 8 , 9 , 20 , 28 , 38 , 40 , 41 , 45 , 60 , and epigastric and/or mesogastric 25 - 27 , 49 , 51 .…”

Section: Resultsmentioning

confidence: 99%

“…Ten patients initially admitted with symptoms of COVID-19 were diagnosed with mesenteric ischemia after an interval of 2-27 days of hospitalization 7 , 10 , 20 , 24 , 28 , 33 , 36 , 57 - 59 . Another 19 patients had previously been diagnosed with COVID-19 but returned to the emergency service or required intra/inter-hospital transfer with gastrointestinal complaints 8 , 9 , 26 , 28 , 30 , 31 , 37 , 39 , 43 - 45 , 47 - 49 , 51 , 60 - 62 . In the series with 24 cases by Sarkardeh et al, one of the inclusion criteria was respiratory signs and symptoms and diagnosis of COVID-19 preceding gastrointestinal manifestations or concomitant diagnosis of COVID-19 and intestinal ischemia or perforation; symptoms and signs of ischemia appeared on average seven days (range 2-21) after initial respiratory symptoms 53 .…”

Section: Resultsmentioning

confidence: 99%

“…Among the 44 selected studies, there were 37 case reports/series, two letters, one review with case descriptions, and four other retrospective studies. The mean age of the 45 patients in the reports, series, and letters was 54.9 years, 66.6 30 of whom were male 7,8, and three did not have their sex reported [50][51][52] . In an Iranian case series of 24 patients, the median age was 61.5 years and 67% of them were male 53 .…”

Section: Resultsmentioning

confidence: 99%

“…Abdominal manifestations, in turn, range from 3% to 39% 7 . Whereas in the general population the incidence of mesenteric ischemia is 0.09%-0.2%, in patients affected by COVID-19 it rises to 1.9%-3.8%, with high rates of associated morbidity and mortality 8 , 9 .…”

Section: Introductionmentioning

confidence: 98%

“…mesenteric ischemia is 0.09%-0.2%, in patients affected by COVID-19 it rises to 1.9%-3.8%, with high rates of associated morbidity and mortality 8,9 .…”

mentioning

confidence: 99%

See 4 more Smart Citations

Acute mesenteric ischemia and COVID-19: an integrative review of the literature

SILVA

Neto

2023

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

The novel coronavirus disease 2019 (COVID-19) has spread rapidly around the world after the first cases were reported in December 2019 in China. Despite the prevention of the symptoms presented, extrapulmonary manifestations were identified. In particular, there was an increase in cases of Acute Mesenteric Ischemia (AMI), raising its incidence to 1.9%-3.8% in infected patients. The aim of this study was to investigate the existence of an association between IMA and COVID-19 through the literature. An Integrative Literature Review was carried out. The research question was “mesenteric ischemia in patients with COVID-19: coincidence or association?”. After searching the database and applying the inclusion and exclusion criteria, 44 were selected for analysis. COVID-19 was confirmed by RT-PCR and imaging tests, gastrointestinal manifestations, alterations and primarily tomographic imaging findings were identified. Most patients were accelerated to laparotomy. As explanations include direct endothelial and injury by the binding of the ACE-2 virus, between hyperinflammation and hypercoagulability, dysregulation of the renin-angiotensin-aldosterone system and factors associated with the severity of the virus. IMA is an emergency with high associated morbidity and mortality, these cases may be a consequence mainly of the thromboinflammatory mechanism associated with SARS-CoV-2. An early diagnosis, diagnosis and diagnoses are crucial to clinical treatment; an assessment regime should be considered in accordance with current evidence and guidelines.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

“…mesenteric ischemia is 0.09%-0.2%, in patients affected by COVID-19 it rises to 1.9%-3.8%, with high rates of associated morbidity and mortality 8,9 .…”

mentioning

confidence: 99%

See 3 more Smart Citations

Acute mesenteric ischemia and COVID-19: an integrative review of the literature

SILVA

Neto

2023

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

show abstract

Isquemia mesentérica aguda e COVID-19: uma revisão integrativa da literatura

SILVA,

FONSECA NETO

2023

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

RESUMO A doença do novo coronavírus 2019 (COVID-19) disseminou-se rapidamente pelo mundo após os primeiros casos serem relatados em dezembro de 2019 na China. Apesar da prevalência dos sintomas respiratórios, manifestações extrapulmonares foram sendo identificadas. Particularmente, houve um aumento de casos de Isquemia Mesentérica Aguda (IMA), elevando sua incidência para 1,9%-3,8% em pacientes infectados. O objetivo deste estudo foi investigar a existência de uma associação entre IMA e a COVID-19 através da literatura. Realizou-se uma Revisão Integrativa da Literatura. A pergunta de pesquisa foi “isquemia mesentérica em pacientes com COVID-19: coincidência ou associação?”. Após a busca na base de dados e aplicação dos critérios de inclusão e exclusão, elegeu-se 44 estudos para análise. A COVID-19 foi confirmada por RT-PCR e exames de imagem, foram identificadas manifestações gastrointestinais, alterações laboratoriais e achados de imagem primordialmente tomográfica. A maioria dos pacientes foi submetida à laparotomia. As explicações incluem lesão endotelial direta pela ligação do vírus ao receptor ECA-2, correlação entre hiperinflamação e hipercoagulabilidade, desregulação do sistema renina-angiotensina-aldosterona e fatores associados à gravidade do quadro. A IMA é uma emergência de alta morbimortalidade associada, nesses casos pode ser consequência principalmente do mecanismo tromboinflamatório associado ao SARS-CoV-2. Um alto nível de suspeita clínica, diagnóstico e tratamento precoces são cruciais diante dessa complicação; um regime de anticoagulação deve ser considerado conforme as evidências e diretrizes vigentes..

show abstract

Isquemia mesentérica aguda e COVID-19: uma revisão integrativa da literatura

Teixeira,

Rosa,

Santos

et al. 2024

Arch. Health

View full text Add to dashboard Cite

Introdução: A infecção pelo SARS-CoV-2 pode provocar inflamação tecidual generalizada, hipercoagulabilidade, lesão endotelial e desregulação do sistema renina-angiotensina-aldosterona, resultando em eventos trombóticos como a isquemia mesentérica aguda (IMA). Fatores de risco incluem idade acima de 45 anos, sexo masculino, hipertensão arterial, diabetes mellitus e obesidade. A IMA é uma condição rara de abdome agudo com manifestações clínicas inespecíficas, como anorexia, diarreia, vômitos e dor abdominal intensa, dificultando seu diagnóstico precoce em casos de COVID-19, pois em 16% dos casos de COVID-19 há sintomas gastrointestinais associados. Exames de imagem, como angiotomografia e angioressonância magnética, são essenciais para o diagnóstico topográfico e etiológico desse tipo de abdome agudo; em casos graves, o tratamento cirúrgico pode ser necessário. O diagnóstico precoce é fundamental para evitar piores prognósticos e indicar o tratamento adequado.

show abstract

Acute mesenteric ischemia in COVID-19: Case report and current understanding

Cited by 3 publications

References 18 publications

Acute mesenteric ischemia and COVID-19: an integrative review of the literature

Acute mesenteric ischemia and COVID-19: an integrative review of the literature

Isquemia mesentérica aguda e COVID-19: uma revisão integrativa da literatura

Isquemia mesentérica aguda e COVID-19: uma revisão integrativa da literatura

Contact Info

Product

Resources

About