Acute Haemolytic Anaemia and Haemorrhagic Diathesis in the Osteomyelofibrotic Syndrome

Lind, Ingemar

doi:10.1159/000206245

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1965

1975

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Cited by 4 publications

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“…L'association à une anémie hémolytique à auto-anticorps a été signalée à plusieurs reprises [6,19,23,29,32,33] parfois même, comme chez l'une de nos malades, l'anémie hémolytique précède l'apparition de la myélosclérose [23]. On connaît également la fréquence de la positivité des tests de la maladie de Marchiafava-Micheli au cours des myéloscléroses [28].…”

Section: Discussionunclassified

Anomalies immunitaires au cours des splénomégalies myéloïdes avec myélosclérose

Boivin¹,

Jf²,

Hakim³

et al. 1974

Acta Haematol

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In a study of 26 cases of myeloid splenomegaly with myelofibrosis, the authors find a large incidence of immunization anomalies, principally: positive latex reaction in 8 cases; monoclonal proteins in 3 cases; anti-erythrocyte antibodies in 6 cases. Anti-muscle antibodies, quantitative changes of the immunoglobulins and the presence of cryoglobulin are also observed. In a control group of 28 patients of identical age distribution, afflicted with various types of hemopathies, immunization anomalies are encountered far more rarely. The significance of immunization anomalies in the course of myeloid splenomegaly with myelosclerosis is discussed especially in its relationship with the development of medullary fibrosis.

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