Activity of endodontic antibacterial agents against selected anaerobic bacteria

Ferreira, Cláudio Santos; Rosa, Odila Pereira da Silva; Torres, Sérgio Aparecido; Ferreira, Flaviana Bombarda de Andrade; Bernardinelli, Norberti

doi:10.1590/s0103-64402002000200008

Cited by 48 publications

(36 citation statements)

References 11 publications

(36 reference statements)

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“…[12] The sealer used may possess some biological, physical, and antimicrobial properties. [345] During obturation it fills the voids and irregularities in between the core material and the dentin such as any lateral, fulcral canals, ramifications, and reticular canals. The conventional irrigation protocols and intracanal medicaments may not be able to completely eradicate bacteria harboring in the dentinal tubules.…”

Section: Introductionmentioning

confidence: 99%

Effect of final irrigating solution on smear layer removal and penetrability of the root canal sealer

Shenoy¹,

Ahmaduddin²,

Bolla³

et al. 2014

J Conserv Dent

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Objective:To evaluate the effect of final rinsing solution on smear layer removal through penetrability of the root canal sealer.Materials and Methods:Each of the 30 teeth selected was decoronated and the root length standardized at 16 mm measured from the apex of the tooth to the cementoenamel junction (CEJ). A size 10-k file was used and working length was determined by subtracting 1mm from the measured length so that the length of the sample was 15mm. A combination of step back and crown down technique was done and apical portion was prepared till H-file no. 30. 3% NaOCl was used during cleaning and shaping of the canals. Finally the teeth were divided into three groups of 10 teeth each. Group-I was irrigated with 17% EDTA, Group-II with TUBLICID plus, and Group-III with Biopure MTAD®. ISO 30 size gutta-percha points were selected as master cones. The Acroseal sealer was mixed with approximated concentration 0.1% fluorescent rhodamine B isothiocyanate dye. Obturation was done and after 48 hours, the roots were sectioned and subjected to confocal laser scanning microscopy.Results:Comparisons among the three groups were done by two-way analysis of variance (ANOVA) and Newman-Keuls multiple post-hoc procedures. The two-way ANOVA showed statistically highly significant results. The maximum depth of sealer penetration was observed in Group II followed by Group III and Group I.Conclusion:The use of -Tubulicid plus as a final irrigant provided better smear layer removal than Biopure a mixture of doxicycline, citric acid and a detergent (Tween 80) (MTAD®) and 17% EDTA.

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“…Ricin specifically and irreversibly inactivates eukaryotic ribosomes, preventing protein synthesis (Dorman and Deans, 2000). The oil obtained by pressing the seeds is a polymer precursor and a solution of RA esters, and is known as castor oil (Ferreira et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…The detergent derived from castor oil, in turn, shows antimicrobial properties in the treatment of necrosis of tooth pulp; its bactericidal activity is similar to sodium hypochlorite (Ferreira et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Addition of increasing doses of ricinoleic acid from castor oil (<i>Ricinus communis</i> L.) in diets of Nellore steers in feedlots

Gandra¹,

Gil²,

Cônsolo³

et al. 2012

J. Anim. Feed Sci.

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The aim of this study was to evaluate the performance and blood parameters of feedlot Nellore cattle fed increasing doses of ricinoleic acid (RA) in the diet. Ninety-six Nellore steers divided into 12 groups of 8 animals were used. The animals were randomly assigned to four treatments: 0, 1, 2, or 4 g of RA/animal/day, with three replicates per treatment. The experimental period consisted of 84 days divided into three 28-day periods preceded by three step-up diets. A quadratic effect was found for average daily gain and final body weight, as well as for leukocyte and lymphocyte counts, and for urea and blood urea nitrogen. A linear effect was observed for albumin, alkaline phosphatase, and gamma glutamyl transferase. The inclusion of 2 g of RA daily improved the performance of feedlot Nellore steers.

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“…Ohara et al evaluated the antibacterial effect of several irrigants and found that Ca(OH) 2 was totally ineffective as saline 39. Studies that compared the effect of various agents showed that Ca(OH) 2 had only a weak effect 40,41,42,43. More recent studies that compared Ca(OH) 2 with other agents reported that Ca(OH) 2 was less effective than others 44,45,46.…”

Section: Reviewmentioning

confidence: 99%

Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part I.In vitrostudies

Kim

2014

Restor Dent Endod

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The goal of endodontic treatment is the prevention and control of pulpal and periradicular infections. Calcium hydroxide (Ca(OH)2) has been widely used in endodontics as an intracanal medicament to eliminate the remaining microorganisms after chemomechanical preparation. The purpose of this article is to review the antimicrobial properties of Ca(OH)2 as an intracanal medicament in root canal treatment. The first part of this review details the characteristics of Ca(OH)2 and summarizes the results of in vitro studies related to its antimicrobial effect. The antimicrobial effect of Ca(OH)2 results from the release of hydroxyl ions when it comes into contact with aqueous fluids. Ca(OH)2 has a wide range of antimicrobial effects against common endodontic pathogens, but is less effective against Enterococcus faecalis and Candida albicans. The addition of vehicles or other agents might contribute to the antimicrobial effect of Ca(OH)2.

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“…In dentistry, membrane material 20 , sealers 17,23,24 and irrigating solution 18 were developed from vegetable polyurethane obtained from castor oil. Additionally, since this polyurethane has been described as being biocompatible, osteoconductor, osteoinductor, antimicrobial, osseointegrable and absorbable 8,16 , it has been used in bone prosthesis, alveolar healing and plastic surgery 16 . In a study conducted by Camargo, et al 3 (2010), the castor oil bean showed less inflammatory response in subcutaneous tissue of rats when compared with calcium hydroxide cement.…”

Section: Introductionmentioning

confidence: 99%

Diametral tensile strength and film thickness of an experimental dental luting agent derived from castor oil

Carmello

Fais²,

Ribeiro

et al. 2012

J. Appl. Oral Sci.

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The need to develop new dental luting agents in order to improve the success of treatments has greatly motivated research.ObjectiveThe aim of this study was to evaluate the diametral tensile strength (DTS) and film thickness (FT) of an experimental dental luting agent derived from castor oil (COP) with or without addition of different quantities of filler (calcium carbonate - CaCO3).Material and MethodsEighty specimens were manufactured (DTS N=40; FT N=40) and divided into 4 groups: Pure COP; COP 10%; COP 50% and zinc phosphate (control). The cements were mixed according to the manufacturers' recommendations and submitted to the tests. The DTS test was performed in the MTS 810 testing machine (10 KN, 0.5 mm/min). For FT test, the cements were sandwiched between two glass plates (2 cm2) and a load of 15 kg was applied vertically on the top of the specimen for 10 min. The data were analyzed by means of one-way ANOVA and Tukey's test (α=0.05).ResultsThe values of DTS (MPa) were: Pure COP- 10.94±1.30; COP 10%- 30.06±0.64; COP 50%- 29.87±0.27; zinc phosphate- 4.88±0.96. The values of FT (µm) were: Pure COP- 31.09±3.16; COP 10%- 17.05±4.83; COP 50%- 13.03±4.83; Zinc Phosphate- 20.00±0.12. One-way ANOVA showed statistically significant differences among the groups (DTS - p=1.01E-40; FT - p=2.4E-10).ConclusionThe experimental dental luting agent with 50% of filler showed the best diametral tensile strength and film thickness.

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Activity of endodontic antibacterial agents against selected anaerobic bacteria

Cited by 48 publications

References 11 publications

Effect of final irrigating solution on smear layer removal and penetrability of the root canal sealer

Addition of increasing doses of ricinoleic acid from castor oil (<i>Ricinus communis</i> L.) in diets of Nellore steers in feedlots

Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part I.In vitrostudies

Diametral tensile strength and film thickness of an experimental dental luting agent derived from castor oil

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