2014
DOI: 10.5395/rde.2014.39.4.241
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Abstract: The goal of endodontic treatment is the prevention and control of pulpal and periradicular infections. Calcium hydroxide (Ca(OH)2) has been widely used in endodontics as an intracanal medicament to eliminate the remaining microorganisms after chemomechanical preparation. The purpose of this article is to review the antimicrobial properties of Ca(OH)2 as an intracanal medicament in root canal treatment. The first part of this review details the characteristics of Ca(OH)2 and summarizes the results of in vitro s… Show more

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Cited by 89 publications
(41 citation statements)
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References 110 publications
(106 reference statements)
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“…10,11 It is especially used in endodontic treatment as a biomaterial for pulp capping agents, root canal sealers, and intracranial medication. [12][13][14] For example, as a pulp capping agent, hydroxyl group in Ca(OH) 2 supplied an alkaline which allowed repair, calcication and mineralizing action. The activity of Ca(OH) 2 correlated to lethal effect of hydroxyl ions on microorganisms, thus it had activity against bacterial, endotoxin, fungal and biolms.…”
Section: Introductionmentioning
confidence: 99%
“…10,11 It is especially used in endodontic treatment as a biomaterial for pulp capping agents, root canal sealers, and intracranial medication. [12][13][14] For example, as a pulp capping agent, hydroxyl group in Ca(OH) 2 supplied an alkaline which allowed repair, calcication and mineralizing action. The activity of Ca(OH) 2 correlated to lethal effect of hydroxyl ions on microorganisms, thus it had activity against bacterial, endotoxin, fungal and biolms.…”
Section: Introductionmentioning
confidence: 99%
“…Calcium hydroxide is used throughout the world since Hermann introduced it to dentistry in 1920 25 . This highly alkaline substance with pH of 12.5 approximately has antibacterial properties and has the ability to induce repair and stimulate hard tissue formation 26 . The antibacterial effect of calcium hydroxide results from the release of hydroxyl ions when it comes into contact with aqueous fluid 27 and its main action is attributed to the effect of these ions on vital tissues 28 .…”
Section: Discussionmentioning
confidence: 99%
“…Calcium hydroxide paste has for many years been the material of choice. Following insertion, the material's microbicidal activity is initiated by the release of hydroxyl ions that not only increases the pH within the root canal system, but directly affects the cytoplasmic membranes, DNA and enzymes of microorganisms . However, some controversy has been linked to calcium hydroxide and its inefficacy against organisms such as E. faecalis and Candida albicans .…”
Section: Endodontic Materialsmentioning
confidence: 99%