2010
DOI: 10.1016/j.nano.2010.01.006
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Accurate quantitation of glutathione in cell lysates through surface-assisted laser desorption/ionization mass spectrometry using gold nanoparticles

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Cited by 57 publications
(36 citation statements)
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“…By using CAP as an internal standard, this SALDI-MS provided spot-to-spot and batch-to-batch variations of less than 10% and 13%, respectively, for the analytes at 10 μM. Minimum problems associated with sweet spots when using inorganic matrices have been reported [33,34]. …”
Section: Sensitivity and Linearitymentioning
confidence: 95%
“…By using CAP as an internal standard, this SALDI-MS provided spot-to-spot and batch-to-batch variations of less than 10% and 13%, respectively, for the analytes at 10 μM. Minimum problems associated with sweet spots when using inorganic matrices have been reported [33,34]. …”
Section: Sensitivity and Linearitymentioning
confidence: 95%
“…Therefore, internal standards are commonly used in MS to improve the accuracy when determining the unknown concentrations of analytes [31,51]. We first compared the quantitative analysis of 5-HIAA with and without the internal standard of NAD by SALDI-TOF MS.…”
Section: Quantitative Analyses Of 5-hiaa Trp 5-htp and 5-ht By Salmentioning
confidence: 99%
“…Previous studies have reported that gold nanoparticles were used as matrixes for the detection of organic compounds, peptides, and drugs with remarkable sensitivities [29][30][31]. The implementation of gold nanoparticles as the matrix was revealed to be an important method for desorption and ionization.…”
Section: Introductionmentioning
confidence: 99%
“…Although the accurate advanced instrumental techniques can be used for the analysis of glutathione oxidative stress biomarker (Chiang et al, 2010), there is a need for the development of inexpensive, field-deployable analytical platforms for disease screening and protection against environmental exposure (Noble et al, 2005), (James et al, 2006). The application of microsensors for screening of biomarkers of oxidative stress has been explored.…”
Section: Microsensor Arraysmentioning
confidence: 99%