Accurate and rapid 3D printing of microfluidic devices using wavelength selection on a DLP printer

Linden, P. van der; Popov, A. M.; Pontoni, Diego

doi:10.1039/d0lc00767f

Cited by 64 publications

(60 citation statements)

References 54 publications

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“…Nordin et al [154] have described a DLP-SLA printer with a custom resin, which has achieved impressive flow channel cross sections with a resolution of 18 × 20 µm. It has been shown that for DLP, better control over the resin polymerisation and quality of the microfluidic devices can be improved by reducing the penetration depth of the UV LED (Light Emitting Diode) light through a combination of wavelength selection and choice of absorber and photo-initiator materials and achieve 37 × 37 µm 2 pixel resolution at a printed layer thickness of 25 µm with a modified desktop printer at 385 nm wavelength [155].…”

Section: D Printingmentioning

confidence: 99%

Fabrication Methods for Microfluidic Devices: An Overview

2021

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Microfluidic devices offer the potential to automate a wide variety of chemical and biological operations that are applicable for diagnostic and therapeutic operations with higher efficiency as well as higher repeatability and reproducibility. Polymer based microfluidic devices offer particular advantages including those of cost and biocompatibility. Here, we describe direct and replication approaches for manufacturing of polymer microfluidic devices. Replications approaches require fabrication of mould or master and we describe different methods of mould manufacture, including mechanical (micro-cutting; ultrasonic machining), energy-assisted methods (electrodischarge machining, micro-electrochemical machining, laser ablation, electron beam machining, focused ion beam (FIB) machining), traditional micro-electromechanical systems (MEMS) processes, as well as mould fabrication approaches for curved surfaces. The approaches for microfluidic device fabrications are described in terms of low volume production (casting, lamination, laser ablation, 3D printing) and high-volume production (hot embossing, injection moulding, and film or sheet operations).

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Section: D Printingmentioning

confidence: 99%

Fabrication Methods for Microfluidic Devices: An Overview

2021

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“…Purely 3D printed chips with the smallest feature sizes require custom 3D printers and resins. The smallest feature sizes are achieved using microstereolithography, 11 modied 3D printers and resins, 24 and high-end or custom 3D printers. 14,16,25,26 Channel sizes down to 18 Â 20 mm have been reported with custom setups.…”

Section: Introductionmentioning

confidence: 99%

Hydrophilic modification of SLA 3D printed droplet generators by photochemical grafting

et al. 2021

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“…Recently, microfluidics chips have been fabricated using a custom-made photopolymer printer based on acrylate PDMS, with an aim to improve the method for fabricating PDMS microfluidics devices with reduced time and cost [232]. With efforts made to produce 3D-printed devices with the exact accuracy using the fabrication technique, Peter et al discovered that a reduction in the penetration depth of UV-LED light (through wavelength selection) in combination with the chosen photoinitiator and absorber materials helped achieve channel dimensions as low as 100 μm using a DLP printer [233]. They also reported that it is possible to have absolute control over the resin polymerization.…”

Section: Prospectsmentioning

confidence: 99%

Recent Developments in 3D Printing of Droplet-Based Microfluidics

Aladese

Jeong

2021

BioChip J

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The advent of microfluidics, especially with the integration of droplet-based systems, has led to significant innovations and outstanding applications in many fields. While this field of study has grown increasingly over the years, the conventional method of fabricating these devices has discouraged their large-scale production, making their commercialization almost impossible. This is because traditional methods of producing droplet-based microfluidics are mostly time-consuming and labor-intensive and involve multiple processes. The emergence of 3D printing has found its application in microfluidics, providing an avenue for ease of fabrication with the aim of overcoming the limitations of conventional methods. While previous studies focused on studying the role of 3D printing in microfluidics, no study has categorically focused on the application of additive manufacturing to droplet-based microfluidics. This paper reviews the various 3D printing techniques associated with droplet-based microfluidics. Furthermore, we identify the salient features, limitations, and material properties of each printing technique while providing certain projections about their future application.

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Accurate and rapid 3D printing of microfluidic devices using wavelength selection on a DLP printer

Abstract: The use of microfluidics on synchrotron X-ray beamlines represents an advanced sample preparation and delivery platform for state-of-the-art X-ray characterization of micro-samples. The recent developments of 3D printing technologies have...

Cited by 64 publications

References 54 publications

Fabrication Methods for Microfluidic Devices: An Overview

Fabrication Methods for Microfluidic Devices: An Overview

Hydrophilic modification of SLA 3D printed droplet generators by photochemical grafting

Recent Developments in 3D Printing of Droplet-Based Microfluidics

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