A Study of Serological Markers of Hepatitis B and C Viruses in Istanbul, Turkey

Erden, Sacide; Büyüköztürk, Suna; Çalangu, Semra; Yilmaz, Gül Ruhsar; Palandüz, Şükrü; Badur, Selim

doi:10.1159/000070757

Cited by 29 publications

(30 citation statements)

References 8 publications

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“…A study from Turkey reported the prevalence of anti-HCV was 2.4% as compared to 14% -16% in our study which is significantly higher [32]. The results of international studies are not comparable to our local results especially in case of HCV, reason being more awareness and better preventive measures, in developed countries.…”

Section: Discussioncontrasting

confidence: 97%

Hepatitis C Status in Karachi, Pakistan, a Five-Year Survey at Civil Hospital, Karachi, Pakistan

Fatima¹,

Shaheen²,

Razzak³

et al. 2015

IJCM

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Hepatitis C virus is associated with Hepatitis C which can be acute or chronic. Acute hepatitis C is usually short term illness that can lead to chronic infection, while chronic hepatitis C is a chronic liver disease leading to cirrhosis, hepatocellular carcinoma and even death. The mode of transmission is mainly parenteral and vertical. Hepatitis C is the leading cause of morbidity and mortality and a serious public health problem, worldwide as well as in Pakistan. There is no vaccine available for hepatitis C so the only way to prevent hepatitis C is by changing behaviors which can spread the disease. Pakistan is also facing a huge burden of this disease. In Pakistan, the frequency of hepatitis C virus infection ranges from 8% -15% in the general population with variations in different parts of the country. The general method of detecting infection with HCV is to observe the presence of antibodies to the virus. The aim of this study was to determine frequency of hepatitis C among general population and to see the increasing frequency in our part. 79840 years and males are affected more than females. Conclusion: Hepatitis C in increasing in our population affecting the young generation between the age of 21 -40 years and male population is affected more than females so a mass screening is needed to know the exact position of the disease as well as awareness programs should be started using media.

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Section: Discussioncontrasting

confidence: 97%

Hepatitis C Status in Karachi, Pakistan, a Five-Year Survey at Civil Hospital, Karachi, Pakistan

Fatima¹,

Shaheen²,

Razzak³

et al. 2015

IJCM

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“…In this study, the frequency of HBV and HCV infections were lower compared to reports from surrounding countries in the region e.g. Iran and Turkey, [15,16] whereas the prevalence of HBV was higher than some countries, e.g. Switzerland.…”

Section: Discussioncontrasting

confidence: 58%

Prevalence of Hepatitis B and C Viruses among Patients Who Underwent Dental Interventions in a Dental Care Units at College of Dentistry, Duhok, Kurdistan

Merza¹,

Selivany²,

Aldoski³

2017

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Background: The aim of this study was to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among patients who attended to undergo dental procedures in a dental care units at College of Dentistry, Duhok, Kurdistan. Furthermore, is it necessary to include routine screening of Hepatitis B surface antigen (HBsAg) and anti-HCV in the dental care setting? Methods: The study was conducted prospectively at Dental care units at College of dentistry in Duhok province from February 2016 -November 2016. The patients' demographic profile was recorded. Blood samples were tested for the presence of HBsAg and anti-HCV at the virology department of Azadi teaching hospital by using enzyme-linked immunosorbent assay (ELISA) technique. The results obtained were analyzed by entering the data in a binary format as a Microsoft Excel spreadsheet. Results: Out of 301 patients, there were 154 (51.16%) male with a mean age of 34.63 years (± 11.04). The prevalence of HBV, HCV and combined HBV + HCV was 1.99%, 0 and 0, respectively. The most common age group in this study was 26-50 yr (220; 66,45%), while the highest sero-positivity of HBsAg (3.17%) was in the age group 0-25 yr. The frequency of HBsAg in male and female was 2.60% and 1.36%, respectively; whereas, the frequency of HCV antibody was zero in both genders. Conclusion: HBV should be considered seriously in patients attending for dental care. Pre-dental intervention screening for HBsAg is a reasonable policy, particularly in younger aged (< 25 year) patients. All dental HCWs should adhere to infection control measures and they should be vaccinated against HBV to reduce the risk of occupational transmission of HBV and HCV. We did not find any case of HCV in this study, which confirms it has a very low prevalence in our region.

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“…In a past epidemiological study, anti-HCV was detected in 21 (1.5%) of 1,374 persons and was more common in residents over 54 years of age in Turkey [14]. Data from past studies on the risk factors for HCV infections in Turkey revealed that a prior history of blood transfusion and nosocomial risk factors accounted for the majority of HCV cases, while IVDU was reported in a small number of HCV cases (4% or less) [13,16,26,27]. Likewise sexual transmission and mother-to-child transmission was low in Turkey [28,29].…”

Section: Discussionmentioning

confidence: 99%

“…Since most of the studies on the epidemiology of HBV and HCV infections in Turkey were conducted in blood donors and risk groups and limited nation-wide data are available in the general population [7,8,12,[15][16][17][18][19], the present population-based, large scale field study was designed to determine seroprevalence of hepatitis B, Delta and C virus infections in relation to risk factors for increased seropositivity in Turkish general population.…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of hepatitis B and C virus infections and risk factors in Turkey: a fieldwork TURHEP study

Tözün

Özdoğan

Çakalǒglu

et al. 2015

Clinical Microbiology and Infection

230

147

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The present study was designed to determine the seroprevalence of hepatitis B and C virus (HBV, HCV) infections and risk factors in the Turkish general population. Participants were enrolled from urban and rural areas of the predetermined 23 EUROSTAT NUTS 2 region. A two-stage stratified sampling method was used to select participants from these regions (n = 5460; 50.9% females; mean (SD) age: 40.8 (14.7) years). Sociodemographics, clinical characteristics and risk factors were recorded at home visits. The seropositivity rates for hepatitis B surface antigen (HBsAg), anti-HCV, anti-HBs and anti-HBc total were 4.0%, 1.0%, 31.9% and 30.6%, respectively. Among HBsAg-positive cases, 94.5% were anti-HBe-positive, 70.2% were HBV-DNA-positive and 2.8% were anti-HDV total positive; 99.1% of HBV infections were of genotype D. Close contact with a hepatitis patient (OR 3.24; 95% CI 2.25-4.66; p < 0.001), living in the southeastern region (OR 2.74; 95% CI 1.7-4.45; p < 0.001), male gender (OR 1.77; 95% CI 1.28-2.46; p < 0.001), being married (OR 1.62; 95% CI 1.02-2.57; p 0.038), educational level less than high school (OR 1.53; 95% CI 1.04-2.26; p 0.03), orodental interventions (OR 1.54; 95% CI 1.01-2.35; p 0.047) and a history of non-disposable syringe use (OR 1.4; 95% CI 1.01-1.96; p 0.045) were significant determinants of HBsAg positivity. Age ≥50 years (OR 2; 95% CI 1.09-4.3; p 0.026) was the only significant predictor of anti-HCV positivity. In conclusion, our findings revealed an HBsAg positivity in 4% and anti-HCV positivity in 1% of the adult population and at least one-third of the population has been exposed to HBV infection in Turkey.

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A Study of Serological Markers of Hepatitis B and C Viruses in Istanbul, Turkey

Cited by 29 publications

References 8 publications

Hepatitis C Status in Karachi, Pakistan, a Five-Year Survey at Civil Hospital, Karachi, Pakistan

Hepatitis C Status in Karachi, Pakistan, a Five-Year Survey at Civil Hospital, Karachi, Pakistan

Prevalence of Hepatitis B and C Viruses among Patients Who Underwent Dental Interventions in a Dental Care Units at College of Dentistry, Duhok, Kurdistan

Seroprevalence of hepatitis B and C virus infections and risk factors in Turkey: a fieldwork TURHEP study

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