A Sensitive and Selective Non-Enzymatic Glucose Sensor based on AuNPs/CuO NWs-MoS₂ Modified Electrode

Abstract

In recent years, copper-based nanomaterials have been widely used in the study of glucose sensors because of its high sensitivity. In this work, a sensitive and selective electrochemical enzyme-free glucose sensor was successfully constructed using a composite of copper oxide nanowires (CuO NWs), molybdenum disulfide (MoS 2 ) and gold nanoparticle (AuNPs). This composite was systematically characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The sensor performance and interface property of the Au electrode modified by NF/AuNPs/CuO-MoS2 were measured by cyclic voltammetry (CV) and chronoamperometric measurements(i-t). Under optimal condition, the proposed sensor shows sensitivity value of 872.71 μA cm −2 mM −1 for glucose, with detection range from 0.5 μM to 5.67 mΜ and detection limit of 0.5 μM. The study also confirms satisfactory selectivity, reproducibility, and stability of the constructed sensor. This NF/AuNPs/CuO NWs-MoS 2 sensor performance toward normal human serum spiked with glucose is determined with RSD less than 4.71%, indicating superior potential for the practical quantitative analysis of glucose in serum samples.

Non-Enzymatic Glucose Sensors Composed of Nanoflower Shaped CuO/Ag/SiNPs Based Composite Material with High Performance

“…Furthermore, this approach could lead to increased conductivity, ampli ed signals, and a synergistic effect for glucose detection. [19][20][21][22] Silica nanoparticles (SiNPs) have been demonstrated to be especially useful for glucose sensing when co-utilized with bimetallic nanoporous materials. [23][24] SiNPs also have potential applications in solar energy converters, microelectronics, photodetectors, displays, and chemical sensors.…”

In Situ Fabrication of Porous Nanostructures Derived from Bimetal-Organic Frameworks for Highly Sensitive Non-Enzymatic Glucose Sensors

“…8,9 Especially, electrochemical non-enzyme glucose sensors with high stability and reusability, is highly desirable. [10][11][12] Metal-organic frameworks (MOFs), composed of organic and inorganic materials, have been reported for multiple applications, such as gas adsorption, catalysis, energy storage, and sensing. [13][14][15][16] MOFs also act as sacrificial templates for derivatives with the advantages of MOFs inherited (large surface area and potential active sites).…”

The Synergistic Effect of Ferrocene and Cu2O to Construct a Sandwich-Type Multi-Signal Amplification Ultra-Sensitive Immunosensor for Carcinoembryonic Antigen Detection

“…Molybdenum disulfide (MoS 2 ) has a structure similar to that of the graphene, thus attracting great attention toward its chemical and electrical properties. [29][30][31][32] Features such as good electrical conductivity, excellent charge transport capability, and high specific surface area have been widely employed in various biosensors. [33][34][35][36] The flower-like MoS 2 nanostructure exhibits peroxidase-like activity and improves the catalytic potential for reduction of H 2 O 2 30 and its large specific surface area can carry more active probes and active areas.…”