A Review of the Use of Tanning Beds as a Dermatological Treatment

Radack, Kyle P.; Farhangian, Michael E.; Anderson, Kristen; Feldman, Steven R.

doi:10.1007/s13555-015-0071-8

Cited by 19 publications

(13 citation statements)

References 65 publications

(61 reference statements)

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“…It is trouble-free to the patients and used extensively. These tanning beds might have significant fluctuation in the UV yield, which is the present challenge in getting a proper dose 53 . Therapy might be self-administered by the patients.…”

Section: Challenges Associated With Phototherapymentioning

confidence: 99%

Untitled

2019

IJPSR

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Psoriasis is autoimmune, hyperproliferative skin disease, which is affecting 2-5% of the population. Etiology of psoriasis is multifactorial. The disease is identified as periodic recycle of events with redscaly skin plaques. The epidemiology of Psoriasis is still unknown. From medication, this disease can only be prevented. Currently, there are many approaches to cure this disease, but still, no approach has completely cured the illness. New treatments are available for psoriasis, which are derived from biotechnology; they are known as biological drugs. The discovery of these new drugs derived from biotechnology prevents the activation of T-cells and targets cytokines. These drugs are less toxic and better functional, so patients, as well as a dermatologist, prefer the use of these biological drugs for the treatment of psoriasis over topical therapy, phototherapy, and systemic therapy. This review gives a detailed explanation of current therapies for the treatment of psoriasis and challenges associated along with it. INTRODUCTION: Psoriasis is a proliferative disorder of the skin with repeating events of hyperkeratosis and inflammation with the worldwide manifestation around 2-5% 1-3. It is characterized by periodic recycling of red and sharp scaly skin plaques 4. Psoriasis is classified into chronic, plaque, guttate, pustular, and erythroderma. Among all the above types, plaque psoriasis is the major one 5-6. The etiology of this disease is multi-factorial that is the union of both environmental, as well as a genetic factor triggering the immune histological changes noticed in the skin 7. However, the cause of psoriasis is still unknown.

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Section: Challenges Associated With Phototherapymentioning

confidence: 99%

Untitled

2019

IJPSR

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“…Less conventional methods of sun exposure, such as tanning bed use, have often been recommended for patients for whom office and/or home phototherapy is not feasible (Radack et al , ). Many tanning facilities are easily accessible and relatively affordable.…”

Section: Practical Uses Associated With Phototherapymentioning

confidence: 99%

Ultraviolet phototherapy for cutaneous diseases: a concise review

Vangipuram

Feldman

2015

Oral Diseases

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Phototherapy is the use of non‐ionizing radiation, primarily in the ultraviolet spectrum, to treat disease. In dermatology, ultraviolet (UV) phototherapy remains an established, lower cost, and often preferred option for many common skin conditions, despite the introduction of newer potent biologics. This article introduces a principal therapeutic modality in the treatment of psoriasis, atopic dermatitis (eczema), vitiligo, and morphea among other diseases where oral manifestations may be present, providing basic information about the use of UVA, UVB, and PUVA. Practical considerations and side effects of phototherapy are described. Phototherapy is an effective treatment for many illnesses and carries a relatively benign side‐effect profile.

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“…For example, UVB light, one form of radiant energy from sunlight, promotes vitamin D generation in the skin (Bouillon, 2017;Hart et al, 2011). UV radiation has been used to treat certain diseases, such as psoriasis, atopic dermatitis, eczema, cutaneous T cell lymphoma, vitiligo, and uremic pruritus (Ada et al, 2005;Archier et al, 2012;Johnson-Huang et al, 2010;Radack et al, 2015). Interestingly, UV light not only causes peripheral effects, but also is associated with various neurological behaviors linked to the CNS.…”

Section: Introductionmentioning

confidence: 99%

Moderate UV Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain

Zhu

Wang

Yao

et al. 2018

Cell

136

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Sunlight exposure is known to affect mood, learning, and cognition. However, the molecular and cellular mechanisms remain elusive. Here, we show that moderate UV exposure elevated blood urocanic acid (UCA), which then crossed the blood-brain barrier. Single-cell mass spectrometry and isotopic labeling revealed a novel intra-neuronal metabolic pathway converting UCA to glutamate (GLU) after UV exposure. This UV-triggered GLU synthesis promoted its packaging into synaptic vesicles and its release at glutamatergic terminals in the motor cortex and hippocampus. Related behaviors, like rotarod learning and object recognition memory, were enhanced after UV exposure. All UV-induced metabolic, electrophysiological, and behavioral effects could be reproduced by the intravenous injection of UCA and diminished by the application of inhibitor or short hairpin RNA (shRNA) against urocanase, an enzyme critical for the conversion of UCA to GLU. These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes.

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A Review of the Use of Tanning Beds as a Dermatological Treatment

Cited by 19 publications

References 65 publications

Untitled

Untitled

Ultraviolet phototherapy for cutaneous diseases: a concise review

Moderate UV Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain

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