A review of biosensors and biologically-inspired systems for explosives detection

Abstract

This article provides a review of the published literature describing the use of biosensors and biologically-inspired systems for explosives detection. The review focusses on the use of antibodies, enzymes, biologically-inspired synthetic ligands and whole-cell biosensors, providing a flavour of the range of technology, formats and approaches that can be used to detect explosives using biological systems.

Synthesis and reactivity of an unexpected highly sensitive 1-carboxymethyl-3-diazonio-5-nitrimino-1,2,4-triazole

“…3 Biosensors use biological molecules usually an enzyme, antibody, or nucleic acid to detect sample molecules of interest 4 via hydrogen bonding, charge charge interactions, and other biochemical interactions. Thus the compounds require functional groups at first, a carboxy or carboxyalkyl group, so that the molecules could be linked to surfaces using amide bridges.…”

Zinc Nanoparticles-equipped Bioelectronic Nose Using a Microelectrode Array for Odorant Detection

“…However, it has been known that the detection limit of bioelectronic noses depends not only on measurement technique and detecting instruments, but also on signals obtained from biological elements. [32][33][34] Thus, it can be assumed that enhancing original biological signals will improve the odorant detection of bioelectronic noses, especially olfactory cell-based biosensors. In our study, we showed the design of a nanoparticle-equipped biosensor for odorant detection.…”

Nanostructured diatom frustule immunosensors

“…Explosive compounds are particularly challenging to detect [7]. The target molecule of interest in the explosive 2,4,6 trinitrotoluene (TNT, molecular weight 227 g/mole).…”