Retinal degenerative diseases lead to blindness due to loss of the “image capturing” photoreceptors, while neurons in the “image processing” inner retinal layers are relatively well preserved. Electronic retinal prostheses seek to restore sight by electrically stimulating surviving neurons. Most implants are powered through inductive coils, requiring complex surgical methods to implant the coil-decoder-cable-array systems, which deliver energy to stimulating electrodes via intraocular cables. We present a photovoltaic subretinal prosthesis, in which silicon photodiodes in each pixel receive power and data directly through pulsed near-infrared illumination and electrically stimulate neurons. Stimulation was produced in normal and degenerate rat retinas, with pulse durations from 0.5 to 4 ms, and threshold peak irradiances from 0.2 to 10 mW/mm2, two orders of magnitude below the ocular safety limit. Neural responses were elicited by illuminating a single 70 μm bipolar pixel, demonstrating the possibility of a fully-integrated photovoltaic retinal prosthesis with high pixel density.

Patients with retinal degeneration lose sight due to gradual demise of photoreceptors. Electrical stimulation of the surviving retinal neurons provides an alternative route for delivery of visual information. We demonstrate that subretinal arrays with 70 μm photovoltaic pixels provide highly localized stimulation, with electrical and visual receptive fields of comparable sizes in rat retinal ganglion cells. Similarly to normal vision, retinal response to prosthetic stimulation exhibits flicker fusion at high frequencies, adaptation to static images and non-linear spatial summation. In rats with retinal degeneration, these photovoltaic arrays provide spatial resolution of 64 ± 11 μm, corresponding to half of the normal visual acuity in pigmented rats. Ease of implantation of these wireless and modular arrays, combined with their high resolution opens the door to functional restoration of sight.

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Australia is among the most fire-prone of continents. While national fire management policy is focused on irregular and comparatively smaller fires in densely settled southern Australia, this comprehensive assessment of continental-scale fire patterning (1997–2005) derived from ~1 km2 Advanced Very High Resolution Radiometer (AVHRR) imagery shows that fire activity occurs predominantly in the savanna landscapes of monsoonal northern Australia. Statistical models that relate the distribution of large fires to a variety of biophysical variables show that, at the continental scale, rainfall seasonality substantially explains fire patterning. Modelling results, together with data concerning seasonal lightning incidence, implicate the importance of anthropogenic ignition sources, especially in the northern wet–dry tropics and arid Australia, for a substantial component of recurrent fire extent. Contemporary patterns differ markedly from those under Aboriginal occupancy, are causing significant impacts on biodiversity, and, under current patterns of human population distribution, land use, national policy and climate change scenarios, are likely to prevail, if not intensify, for decades to come. Implications of greenhouse gas emissions from savanna burning, especially seasonal emissions of CO2, are poorly understood and contribute to important underestimation of the significance of savanna emissions both in Australian and probably in international greenhouse gas inventories. A significant challenge for Australia is to address annual fire extent in fire-prone Australian savannas.

Considerable research has been undertaken over the past two decades to apply remote sensing to the study of fire regimes across the savannas of northern Australia. This work has focused on two spatial scales of imagery resolution: coarse-resolution NOAA-AVHRR imagery for savanna-wide assessments both of the daily distribution of fires ('hot spots'), and cumulative mapping of burnt areas ('fire-scars') over the annual cycle; and fine-resolution Landsat imagery for undertaking detailed assessments of regional fire regimes. Importantly, substantial effort has been given to the validation of fire mapping products at both scales of resolution. At the savanna-wide scale, fire mapping activities have established that: (1) contrary to recent perception, from a national perspective the great majority of burning in any one year typically occurs in the tropical savannas; (2) the distribution of burning across the savannas is very uneven, occurring mostly in sparsely settled, higher rainfall, northern coastal and subcoastal regions (north-west Kimberley, Top End of the Northern Territory, around the Gulf of Carpentaria) across a variety of major land uses (pastoral, conservation, indigenous); whereas (3) limited burning is undertaken in regions with productive soils supporting more intensive pastoral management, particularly in Queensland; and (4) on a seasonal basis, most burning occurs in the latter half of the dry season, typically as uncontrolled wildfire. Decadal fine-resolution fire histories have also been assembled from multi-scene Landsat imagery for a number of fire-prone large properties (e.g. Kakadu and Nitmiluk National Parks) and local regions (e.g. Sturt Plateau and Victoria River District, Northern Territory). These studies have facilitated more refined description of various fire regime parameters (fire extent, seasonality, frequency, interval, patchiness) and, as dealt with elsewhere in this special issue, associated ecological assessments. This paper focuses firstly on the patterning of contemporary fire regimes across the savanna landscapes of northern Australia, and then addresses the implications of these data for our understanding of changes in fire regime since Aboriginal occupancy, and implications of contemporary patterns on biodiversity and emerging greenhouse issues.

Non-dispersive infra-red (NDIR) gas detection has enjoyed widespread uptake as a result of development of devices in the standard miniature format for gas sensors, consisting of a cylinder with external dimensions of 20 mm diameter x 16.5 mm height. We present a new design for such a sensor, making use of low-cost injection moulding technology. The design pays particular attention to the problem of maintaining a high optical throughput while providing an acceptable optical pathlength for gas detection. A detailed analysis of the design is presented, with the results of optical raytracing, showing a raytrace estimate for 4% of the total emitted radiation reaching each of two separated detector elements and a pathlength of 32 mm. Finally, we show experimental results obtained with as-manufactured devices, with a short-term limit of detection for carbon dioxide (CO 2 ) estimated at 1 ppm or a noise equivalent absorption (NEA) of 3 x 10 -5 AU. Highlights New design of non-dispersive infra-red (NDIR) sensor for CO 2 and other gases  Standard miniature format for gas sensors -a cylinder 20mm D x 16.5mm H  Raytrace -estimated 32mm pathlength  Manufactured in volume using gold-coated injection-moulded reflective optics  Short-term limit of detection 1ppm CO 2 , noise equivalent absorbance 3x10 -5 AU

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This article provides a review of the published literature describing the use of biosensors and biologically-inspired systems for explosives detection. The review focusses on the use of antibodies, enzymes, biologically-inspired synthetic ligands and whole-cell biosensors, providing a flavour of the range of technology, formats and approaches that can be used to detect explosives using biological systems.