A Pharmacognostic and Pharmacological Review on Alstonia Scholaris

Kanase, Vanita; Mane, Deepali

doi:10.22159/ajpcr.2018.v11i12.28124

Cited by 6 publications

(4 citation statements)

References 16 publications

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“… Alstonia scholaris known to possess various activities like analgesic, anticancer, hepatoprotective, anti-inflammatory, antibacterial, wound healing. These can be used in arthritis, diabetic conditions [97].…”

Section: Lupeol Acetate and α-Amyrin Acetatementioning

confidence: 99%

Impending Contraceptives That Might Be a Positive Methodology Towards the Male Contraception

et al. 2022

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The total population has been developing dramatically; be that as it may, right now, the decisions for male contraception are restricted. This study investigates continuous explores of male contraceptives. This study article is primarily based on the thought of contraception that must be needed toward the increasing population and giving the ideal strategy to control the fertility of humans and animals. This review featured the recent oral male contraceptives that may be revolutionary products in our world as means of contraception. The audit article considers that these contraceptives are customarily utilized for their spermicidal activities and their fundamental hormones of the awkwardness for fertility and the mechanism of activity of the impact of the antifertility of contraceptives. The present study offers up-to-date data gathered on the contraceptives used for anti-fertility activity in males. The goal of this study is to spotlight the work on the anti-fertility effect of contraceptives. Therefore these products can provide options and lowering fertility would be higher than different contraceptives. This article can also assist investigators in developing the newer contraceptive preparation for anti-fertility activity in males. The innovations in this field are important to focus on current, more intense medication having a less detrimental effect on the body function and that can be administrable on its entity, less expensive, and quite reversible.

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Section: Lupeol Acetate and α-Amyrin Acetatementioning

confidence: 99%

Impending Contraceptives That Might Be a Positive Methodology Towards the Male Contraception

et al. 2022

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“…could be attributed either to the reducing agents such as phenol groups and the number or/and the position of the hydroxyl molecule on these groups [47]. Radial scavenging and antioxidant potential of leaves were ascribed to its phenolic and flavonoid content as described in previous studies by Kanase and Mane (2018) [48].…”

Section: Fig 5: Reducing the Power Of Methanol Extract (Me) And Aqueous Extract (Ae) Of G Montana In Comparison With Ascorbic Acid (Std) mentioning

confidence: 99%

Antioxidant Studies on Methanol and Aqueous Extracts of Gymnosporia Montana Plant

Ansari

Chandel

2018

Int J Pharm Pharm Sci

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Objective: The main objective of this study was to evaluate the free radical scavenging activity of methanol (70%) and aqueous extract of G. montana leaves which is a traditionally used herb known for its hepatoprotective activity. Methods: The in vitro antioxidant activity of G. montana extract was determined using 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH), 2,2′-azinobis-(3-ethylbenzothiaziline-6-sulfonate (ABTS), Hydrogen peroxide scavenging activity, Superoxide anion radical scavenging activity and Reducing Power ability at three different concentrations (1.78µg/ml, 3.57µg/ml and 7.14µg/ml). Results: The Results revealed similar observations between the methanol and aqueous extract with respect to standard and showed potent antioxidant activity. Ascorbic acid was used as a standard, which showed IC50 value 4.71µg/ml, whereas, methanol and aqueous extract showed 5.08 µg/ml and 5.69 µg/ml. Three different concentrations were used which showed a dose-dependent non-significant increase in percent inhibition. Conclusion: Findings indicate that this plant is a good source of antioxidant and can be used for the treatment of diseases as such medicinal plant extracts are natural products and they are comparatively safe, eco-friendly, less expensive and locally available. Hence, the validation of the effects of these herbal remedies will have to be undertaken for their wider acceptance.

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“…Other research groups followed suit. A large number of phytoconstituents, particularly indole alkaloids, have been isolated from different parts of plants of Alstonia species [7][8][9][10][11][12][13] ; though more remain to be characterized.…”

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confidence: 99%

“…In view of the medicinal importance of Alstonia species, research work is still continuing in different countries [10][11][12][13][14][15][16][17][18][19][20][21][22][23] . A. scholaris plant formulations are used to treat diarrhea 10 , wounds and earache 14 , fever 15 .…”

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confidence: 99%

Untitled

2020

IJPSR

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We report the phyto-pharmacognostic evaluation and HPTLC fingerprinting profile of the methanolic extract of Saptaparṇa [Alstonia scholaris (L.) R. Br.] leavesunaffected and gall-affected, collected in January 2019. Materials and Methods: Physicochemical parameters and phytochemical screening were done by standard procedures. HPTLC fingerprinting profile of the methanolic extracts of dried leaves and dried leaves with gall was performed on pre-coated TLC silica gel 60F 254 plates with hexane: EtOAc: MeOH: formic acid (5:4.5:0.5:0.5 v/v) as developing solvent, with observation at 254 and 366 nm. Results: Some of the leaves had 15-20 galls on both surfaces. Powder Microscopy of the bitter-tasting green color leaf powder showed a group of epidermal cells, unicellular trichomes, elongated stone cells in the group, prismatic calcium oxalate crystals, single-layered fibers, reticulate vessels, anomocytic stomata, and reddish-brown color tannin matter; epidermis of gall cells, insect body in affected leaves. Phytochemical screening revealed the presence of alkaloids, carbohydrates, terpenoids/steroids, phenolic compounds/ tannins, but an absence of reducing sugars and flavonoids. A large number of bands were observed on HPTLC chromatogramsmany showed red fluorescence at 366 nm. Methanolic extracts of leaves, with or without galls, gave similar results as regards the number and position of the bands, an additional band of low R f was discernible in the extract of leaves with gall. However, there were some instances of variations in peak intensities, a few exhibiting marked differences. Conclusion: There is a clear indication that there is a significant difference between concentrations of some phytoconstituents in leaves with and without galls. The phyto-pharmacognostical studies and HPTLC fingerprinting profiles can be used for the authentication and identification of the leaves of this medicinally important plant. INTRODUCTION: There is a global resurgence of interest in traditional Asian schools of medicine, which use plant-based materials and their formulations.

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A Pharmacognostic and Pharmacological Review on Alstonia Scholaris

Cited by 6 publications

References 16 publications

Impending Contraceptives That Might Be a Positive Methodology Towards the Male Contraception

Impending Contraceptives That Might Be a Positive Methodology Towards the Male Contraception

Antioxidant Studies on Methanol and Aqueous Extracts of Gymnosporia Montana Plant

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