A novel non-synonymous SNP of the COLX gene and its association with duck reproductive traits

Chang, Mu-Tzu; Cheng, Y. S.; Huang, Mu-Chiou

doi:10.1016/j.mcp.2012.05.003

Cited by 11 publications

(12 citation statements)

References 33 publications

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“…No homozygous GG genotype was detected at the 509G>T loci. There are two possible explanations for this finding: 1) the frequency of the G allele may be low as a result of artificial selection, migration, and genetic drift, such that GG individuals are eliminated through natural selection; or 2) the sample size in this study may have been too small to detect GG individuals (Chang et al, 2012).…”

Section: Discussionmentioning

confidence: 86%

“…IAG is secreted by the androgenic gland, which is an endocrine organ unique to males (Ventura et al, 2011). The cDNA sequence of IAG has been cloned in several commercially important crustaceans (Manor et al, 2007;Sroyraya et al, 2010;Mareddy et al, 2011;Zhang et al, 2011;Chang et al, 2012;Ma et al, 2013). However, the distribution of the IAG gene in the tissues of crustaceans differs.…”

Section: Introductionmentioning

confidence: 99%

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Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

Fj¹,

Fw²,

Hk³

et al. 2015

Genet. Mol. Res.

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ABSTRACT. Increasing evidence suggests that the insulin-like androgenic gland hormone (IAG) gene plays an important role in male sexual differentiation, metabolism, and growth in crustaceans. In the present study, we isolated the full-length genome sequence of IAG by genome walking based on the cDNA sequence in Macrobrachium nipponense. Four novel single nucleotide polymorphisms (SNPs) were studied, including 509G>T, 529G>T, 590A>T in intron 1, and 2226A>G in intron 2. The association of genetic variation with growth traits [body length (BL) and body weight (BW)] was analyzed. Individuals with GG geno- 5911 SNPs of the IAG gene in Macrobrachium nipponense©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (2): 5910-5921 (2015) type at locus 2226A>G maintained higher mean BL (P < 0.01) and BW (P < 0.05) than AA and GA individuals. These results suggest that IAG SNPs may be useful molecular markers for selecting growth traits in M. nipponense.

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Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

Fj¹,

Fw²,

Hk³

et al. 2015

Genet. Mol. Res.

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“…Genetic approaches may have permanent effects and more sustainable, because improved genetic characteristic inherited from generation to generation. Molecular identification using loci-associated genetic that economically important, can be used to enhance genetic quality in livestock (Chang et al 2012). Identification and utilization candidate of potential genes that associate with reproduction and profitable is important to improve poultry breeding programs (Basumatary et al 2019).…”

Section: Introductionmentioning

confidence: 99%

“…The egg production is also controlled by genes. In duck reproduction, several genes involved in reproductive efficiency characteristics such as X-collagen or COLX gene (Chang et al 2012) and prolactin (PRL) gene (Li et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Short Communication: Prolactin and x-collagen genes polymorphism in Central Javanese local ducks, Indonesia

Susanti

Yuniastuti

2020

Biodiversitas

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Abstract. Susanti R, Yuniastuti A. 2020. Short Communication: Prolactin and x-collagen genes polymorphism in Central Javanese local ducks, Indonesia. Biodiversitas 21: 605-610. Genetic conservation is an effective approach to preserve unique and protected species in Indonesia, including indigenous duck (Anas platyrhynchos Linnaeus, 1758). One of the most important things is an identification effort by studying genetic characteristics to support genetic resource conservation programs. This study aim was to analyze the genetic polymorphisms of Central Javanese local duck based on prolactin (PRL) and collagen-x (COLX) genes. A total of 35 local ducks in Central Java was collected as samples, the duck’s calamus feathers were taken for tissue DNA isolation. Polymorphism analysis of PRL and COLX genes were performed using single nucleotide polymorphism (SNP) markers and PCR-RFLP method. The amplicons were then digested with DraI restriction enzyme (AhaIII) (5'TTT/ AAA) for PRL gene, and HaeIII (BsuRI) enzyme (5'GG/ CC-3 ') for COLX gene. The genotype was determined based on RFLP PCR amplicon band results from each target gene. For each gene, data on genotype frequencies, allele frequencies, expected heterozygosities (HE), and Hardy-Weinberg equilibrium were analyzed using PopGene32 software. Based on the PRL gene, there were 25 ducks (71.43%) with BB genotype and 10 ducks (28.57%) with AB genotype. While based on the COLX gene, as many as 25 ducks (71.43%) had TT genotypes, 9 ducks (25.71%) had TC types and 1 duck (1.86%) had CC types. Both PRL and COLX genotypes were clustered the Central Javanese local ducks into 5 haplotypes (A-E). The high allele frequency has belonged to B allele (85.71%) of the PRL gene and T allele (84.25%) of the COLX gene that showed high egg production and quality. Allele B (PRL gene) and T allele (COLX gene) could be predicted as weight eggs’ alleles marker.

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“…Therefore, identification of genetic markers associated with these traits can promote selection of economically favorable traits (Chang et al 2012). Sirtuins, the silent information regulator 2 (Sir2) gene family, belong to the class III nicotinamide adenine dinucleotide (NAD)-dependent deacetylases (Guarente 2007).…”

Section: Introductionmentioning

confidence: 99%

Expression analysis, single nucleotide polymorphisms within SIRT4 and SIRT7 genes and their association with body size and meat quality traits in Qinchuan cattle

Gui

Xin

Wang

et al. 2016

Journal of Integrative Agriculture

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Silent information regulator 2 (Sir2) proteins, or sirtuins, are nicotine adenine dinucleotide (NAD)-dependent deacetylases that connect metabolism with longevity in lower organisms. In mammals, there are seven Sir2 homologs, namely, silent information regulators (SIRT1-7). SIRT4 and SIRT7 genes play a crucial role in regulating lipid metabolism, cellular growth and metabolism. This suggests that they are potential candidate genes for affecting body size and meat quality traits in animals. Hence, this study aimed to detect genetic variations of both SIRT4 and SIRT7 bovine genes in Qinchuan cattle, and to evaluate the effect of these variations on economically important body size and meat quality traits. Expression analysis using quantitative real-time PCR (qPCR) indicated that SIRT4 and SIRT7 were broadly expressed in all thirteen studied tissues. The expression of SIRT4 was higher in liver, muscle, and in subcutaneous fat tissue. In the case of SIRT7, the expression was higher in lung, abomasum, and subcutaneous fat. Using DNA sequencing, a total of three single nucleotide polymorphisms (SNPs) were identified within SIRT4 and SIRT7 genes in 468 Qinchuan cattle. These included one novel SNP within 3´ untranslated regions (UTR) of SIRT4 (SNP1: g.13915A>G) and two novel synonymous substitutions in SIRT7 (SNP2: g.3587C>T and SNP3: g.3793T>C). Statistical analyses indicated that all three SNPs could significantly influence some body size and meat quality traits in Qinchuan cattle. These novel findings will provide a background for application of bovine SIRT4 and SIRT7 genes in the selection program of Chinese cattle.

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A novel non-synonymous SNP of the COLX gene and its association with duck reproductive traits

Cited by 11 publications

References 33 publications

Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

Short Communication: Prolactin and x-collagen genes polymorphism in Central Javanese local ducks, Indonesia

Expression analysis, single nucleotide polymorphisms within SIRT4 and SIRT7 genes and their association with body size and meat quality traits in Qinchuan cattle

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