A new approach to study medicinal plants with tannins and flavonoids contents from the local knowledge

Araújo, Thiago Antǒnio de Sousa; Alencar, Nélson Leal; Amorim, Elba Lúcia Cavalcanti de; Albuquerque, Ulysses Paulino

doi:10.1016/j.jep.2008.07.032

Cited by 186 publications

(81 citation statements)

References 43 publications

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“…1.3 ± 1.1 1.6 ± 2.5 3.5 ± 2.1 3.3 ± 1.7 3.5 ± 2.5 5.7 ± 3.6* C-m 1.6 ± 0.8 0.2 ± 0.3 1.8 ± 1.3 1.6 ± 1.2 1.5 ± 0.6 11.5 ± 7. In addition, the occurrence of other phytochemicals, such as tannins, saponins, coumarins and alkaloids, in the leaves of J. mollissima (Araújo, Alencar, Amorim, & Albuquerque, 2008;Melo et al, 2010) may be related to their larvicidal activity. Tannins significantly reduce the growth and survival of larvae, as these molecules inactivate digestive enzymes and give rise to a tannin-protein complex of difficult digestion (Cavalcante, Moreira, & Vasconcelos, 2006).…”

Section: Resultsmentioning

confidence: 99%

Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of Jatropha mollissima (Pohl) Baill

Araujo

Costa

Oliveira

et al. 2018

Acta Sci. Biol. Sci.

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ABSTRACT. The present study aimed to evaluate the larvicidal effect of aqueous leaf extract from Jatropha mollissima on the larvae of Aedes aegypti and analyze its cytotoxic and genotoxic activity in the Allium cepa test. Larvae of the mosquito were exposed to the negative and positive controls (distilled water and diflubenzuron, 0.003 mg mL -1 , respectively) and to leaf extract concentrations of 0.001, 0.005, 0.01, 0.02, 0.04, 0.06, 0.08 and 0.1 mg mL -1 . The mortality rate was evaluated every 24 hours over five days. For the cytotoxic and genotoxic analyses, roots of A. cepa were exposed to the negative (distilled water) and positive control (trifluralin, 0.84 ppm) and to different leaf extract concentrations (0.01, 0.1, 1 and 10 mg mL Efeitos larvicida, citotóxico e genotóxico do extrato aquoso das folhas de Jatropha mollissima (Pohl) Baill RESUMO. O presente estudo teve como objetivo avaliar o efeito larvicida do extrato aquoso das folhas de Jatropha mollissima sobre as larvas de Aedes aegypti e analisar sua atividade citotóxica e genotóxica no teste Allium cepa. As larvas do mosquito foram expostas aos controles negativo e positivo (água destilada e diflubenzuron, 0,003 mg mL -1 , respectivamente) e ao extrato foliar nas concentrações de 0,001; 0,005; 0,01; 0,02; 0,04; 0,06; 0,08 e 0,1 mg mL -1 . A taxa de mortalidade foi avaliada a cada 24horas durante cinco dias. Para as análises citotóxica e genotóxica, as raízes de A. cepa foram expostas ao controle negativo (água destilada) e positivo (trifluralina, 0,84 ppm) e nas concentrações (0,01; 0,1; 1 e 10 mg mL -1 ) do extrato foliar por 24 horas. Análises estatísticas foram realizadas pelo teste de Kruskal-Wallis (p < 0,05). O extrato foliar apresentou atividade larvicida promissora nas concentrações de 0,08 e 0,1 mg mL -1 , e nenhuma das concentrações avaliadas em A. cepa exibiu efeito citotóxico ou genotóxico. Uma vez demonstrada a ação larvicida de J. mollissima e a ausência de toxicidade celular, mais estudos são recomendados para determinar o mecanismo de ação do extrato como um possível larvicida natural.

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Section: Resultsmentioning

confidence: 99%

Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of Jatropha mollissima (Pohl) Baill

Araujo

Costa

Oliveira

et al. 2018

Acta Sci. Biol. Sci.

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“…These are produced in plants serving variety of functions like defense against pathogens and different forms of environmental stress, e.g., heat stress, moisture stress, UV radiation. 19 Tannins and flavonoids also possess therapeutic uses due to their anti-inflammatory, antifungal, antioxidant, and healing properties. 20 Shikimic acid is an intermediate of the shikimic acid pathway 21 implicated in the synthesis of aromatic metabolites in plants and microorganisms.…”

Section: Discussionmentioning

confidence: 99%

Comparative Study on Two Variants of Laghupanchamula (A Compound Ayurvedic Formulation) for Important Groups of Phytochemicals and Antioxidant Activity

Ghildiyal¹,

Joshi²,

Joshi³

2017

Journal of Drug Research in Ayurvedic Sciences

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Introduction: Laghupanchamula is a compound formulation prepared by combinations of roots of five herbs. Two variants of Laghupanchamula have been described in Ayurvedic classics where beside four common herbs fifth one is either Gokshura (Tribulus terrestris L.) or Eranda (Ricinus communis L.). The objective of the study is to make comparison between two variants of Laghupanchmula with respect to important group of phytochemicals and antioxidant activity to corroborate the science behind their therapeutic utility.

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“…In this study the active compounds were not identified. However, the presence in this species of tannins, flavonoids and of saponins (serjanosides) has been reported (Teixeira et al 1984;de Sousa Araújo et al 2008). S. meridionalis, a species phytochemically not described, exhibited deterrent activity against E. paenulata and M. persicae (Hemiptera: Aphididae) when its ethanolic leaf extracts were assayed.…”

Section: Binding To Glycoconjugates On the Surface Of Epithelial Cellmentioning

confidence: 98%

Bioactive Natural Products from Sapindaceae Deterrent and Toxic Metabolites Against Insects

Díaz¹,

Rossini²

2012

Insecticides - Pest Engineering

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A new approach to study medicinal plants with tannins and flavonoids contents from the local knowledge

Cited by 186 publications

References 43 publications

<b>Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of <i>Jatropha mollissima</i> (Pohl) Baill

<b>Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of <i>Jatropha mollissima</i> (Pohl) Baill

Comparative Study on Two Variants of Laghupanchamula (A Compound Ayurvedic Formulation) for Important Groups of Phytochemicals and Antioxidant Activity

Bioactive Natural Products from Sapindaceae Deterrent and Toxic Metabolites Against Insects

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