2021
DOI: 10.4103/ccd.ccd_466_20
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Abstract: Background: The oral squamous cell carcinoma (OSCC) often affects elderly aged adults, who had long-term tobacco exposure. In the recent past decade, there is an increasing incidence of OSCC in younger individuals, who had less tobacco association. Aim: The aim of this study is to examine the risk factors and to assess and compare the clinicopathological features and prognosis of OSCC in young patients with the older group patients. Materials and Methods:… Show more

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Cited by 7 publications
(3 citation statements)
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“…More than 350,000 new cases of OSCC are diagnosed every year worldwide, but the poor prognosis of oral cancer has not improved significantly in recent decades [ 2 ], with a tendency to worsen even for the young population [ 3 ]. The 5-year survival rate of patients with oral cancer is less than 50% [ 4 ], and the therapies applied, including surgery, radiotherapy, and chemotherapy, lead to a significant reduction in the quality of life [ 5 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…More than 350,000 new cases of OSCC are diagnosed every year worldwide, but the poor prognosis of oral cancer has not improved significantly in recent decades [ 2 ], with a tendency to worsen even for the young population [ 3 ]. The 5-year survival rate of patients with oral cancer is less than 50% [ 4 ], and the therapies applied, including surgery, radiotherapy, and chemotherapy, lead to a significant reduction in the quality of life [ 5 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…It usually affects patients in the sixth to eight decades of life, despite recently there is an increasing incidence of OSCC in younger individuals. Elderly OSCC patients generally report usual exposure to well-known risk factors for cancer insurgence, such as tobacco or alcohol consumption [ 1 ]. The tongue is the most common site of OSCC insurgence despite the age of presentation, even though some authors reported the alveolar process as a predilection OSCC site in elderly patients [ 2 ].…”
Section: Introductionmentioning
confidence: 99%
“…OSCC is commonly preceded by oral potentially malignant disorders (OPMDs), of which oral leukoplakia (OL) is the most common [ 3 ]. In addition, patients affected with OSCC can develop loco-regional recurrence during aftercare at a rate of 40% [ 4 ], and recent studies reported higher recurrence percentages in younger patients compared to elderly ones [ 1 ]. The clinical and histological features of a single OPMD do not provide sufficient information for identifying patients who will develop OSCC during follow-up.…”
Section: Introductionmentioning
confidence: 99%