A direct intercomparison of two whole-body monitors in the measurement of the absorption of an oral dose of vitamin B₁₂ labelled with ⁵⁷Co and ⁵⁸Co

Abstract

The performance of two whole-body monitors in estimating the absorption of an oral dose of cyanocobalamin labelled with WO and WO was compared directly.Measurements were made on the same subjects using both monitors: (a) on the day of administration, when the variation in the counting rate was similar for the monitors: and (b) seven days later when the percentage absorption was estimated. Good agree. ment was obtained. Factors influencing the accuracy of the measurements are compared and discussed.