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In order to ascertain what effect tonsillectomy may have in the treatment of children and adolescents with recurring psoriasis vulgaris, refractory to topical therapy and courses of penicillin, and triggered by infection, and also to test a possible correlation between tonsillitis and exacerbations of psoriasis, a retrospective study of the course of psoriasis after tonsillectomy, using charts and questionnaires, was undertaken in 74 psoriatic patients. Each patient served as his own control. The average age of the patients at tonsillectomy and the duration of psoriasis were 14.2 years and 4.5 years, respectively, while the average follow-up period was 4.5 years. The clearing of the psoriasis was statistically significant (p < 0.01) as it occurred throughout the entire follow-up period in one-third of the patients, while an additional third noticed considerable improvement of their psoriasis. After trying topical therapies of various sorts as well as courses of penicillin, tonsillectomy might be considered for recurring, refractory psoriasis vulgaris in children and adolescents.

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In 15 patients with pernicious anemia, the fractional retention of 58Co‐cyanocobalamin (FRB12) without administration of intrinsic factor (IF) averaged 4.9% (range 0–12.7). With administration of IF, FRB12 averaged 32.7% (range 26.6–42.3) in the patients and 65.6% (range 38.8–84.6) in 16 control subjects. The gut transit time for vitamin B12 was evaluated from the excretion of radiopaque pellets given concomitantly with the 58Co‐vitamin B12. The retention of the pellets was positively correlated to that of the non‐absorbed 58Co‐B12. Control of the gut transit time is recommended at each examination of FRB12 in order to avoid falsely high values due to the retention of non‐absorbed 58Co‐B12. We found a good reproducibility of FRB12 when determined in fasting subjects, and it is therefore unnecessary to give the patients a B12‐free meal prior to the examination. As the FRB12 in all probability is only a little lower than the fractional absorption, the present method is applicable for the determination of B12 absorption.