A comprehensive review of liquid chromatography hyphenated to post-column photoinduced fluorescence detection system for determination of analytes

Nadeem, Muhammad; Hussian, Irshad; Ali, Amjad; Hussain, Tajamal; Intisar, Azeem; Haq, Iftikhar Ul; Subhani, Qamar; Hedar, Mateen; Zhong, Jiu-Chang; Asif, Muhammad; Guo, Dandan; Cui, Hairong; Zhu, Yan

doi:10.1016/j.arabjc.2022.104091

Cited by 27 publications

(1 citation statement)

References 165 publications

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“…Multidimensional chromatography is used widely in the field of the biomedical and pharmaceutical industry due to the complex nature of the analyte and decreased amount present in the biological matrix [50][51][52] (Figure 1). High selectivity and accurate systems are needed with high reliance to determine such compounds [53,54].…”

Section: Biomedical and Pharmaceutical Applicationsmentioning

confidence: 99%

Multidimensional Chromatography and Its Applications in Food Products, Biological Samples and Toxin Products: A Comprehensive Review

et al. 2022

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Food, drugs, dyes, extracts, and minerals are all made up of complex elements, and utilizing unidimensional chromatography to separate them is inefficient and insensitive. This has sparked the invention of several linked chromatography methods, each of them with distinct separation principles and affinity for the analyte of interest. Multidimensional chromatography consists of the combination of multiple chromatography techniques, with great benefits at the level of efficiency, peak capacity, precision, and accuracy of the analysis, while reducing the time required for the analysis. Various coupled chromatography techniques have recently emerged, including liquid chromatography–gas chromatography (LC–GC), gas chromatography–gas chromatography (GC–GC), liquid chromatography–liquid chromatography (LC–LC), GCMS–MS, LCMS–MS, supercritical fluid techniques with chromatography techniques, and electro-driven multidimensional separation techniques. In this paper, the different coupled chromatography techniques will be discussed, along with their wide spectrum of applications for food, flavor, and environmental analysis, as well as their usefulness for the pharmaceutical, color, and dyes industries.

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