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Abstract

The experiments have demonstrated the importance of copolymer structure on the biological properties of surface modified nanospheres. Modified copolymers, which possess comparable properties to their unmodified forms, could be used in nanosphere systems where antibody fragments can be attached to the copolymers, thereby producing nanospheres which target to specific body sites.

Preparation and characterization of cationic Pluronic for surface modification and functionalization of polymeric drug delivery nanoparticles

“…Formation of amine end groups on PEO molecules can be achieved by various methods which usually involve two or more reaction steps. One of those is the conversion of the hydroxyl groups to halide or sulfonyl ester, followed by a reaction with excess amount of ammonia [24,25]. Another strategy for the introduction of amine functionality is by activating the hydroxyl groups followed by conjugation with diamines and polyamines [26,27].…”

Research on the Repeated Use of Novel Ferrocene-Tagged Nanomaterial for Determination of Glucose

“…Norman et al [5] pioneered the development of nanomaterial-based polystyrene in 1993. Neal et al [6] have developed physical and biological properties of polystyrene nanospheres with radiolabeled. In recent years, there has been increasing interest in enzyme immobilization of nano-and microparticles due to easier operational control.…”

Immobilization of acetylcholinesterase on Pt(ii) and Pt(iv) attached nanoparticles for the determination of pesticides

“…After Norman and et al [8] pioneered the development of nanomaterial-based polystyrene in 1993, today many researchers have developed immobilization properties of polystyrene nanospheres [9][10][11]. One of the immobilized species is covalent immobilization.…”

“…6,7 After Norman et al 8 pioneered the development of nanomaterial-based polystyrene in 1993, many researchers have since developed the immobilization properties of polystyrene nanospheres. [9][10][11] One method to achieve immobilized species is covalent immobilization. The covalent immobilization of an enzyme can protect its conformation, thus leading to better activity and stability.…”