Nickel speciation in cocoa infusions using monolithic chromatography – Post-column ID-ICP-MS and Q-TOF-MS

Peeters, Kelly; Zuliani, Tea; Žigon, Dušan; Milačić, Radmila; Ščančar, Janez

doi:10.1016/j.foodchem.2017.03.050

Cited by 24 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In human milk, nickel was found to be associated with high molecular mass biomolecules, probably caseins, lactotransferrin, serum albumin or immunoglobulins. Recently, nickel (II), nickel gluconate and nickel citrate complexes were found in cocoa infusions (Peeters et al., 2017). Nickel citrate and nickel malate complexes account for 99% of the nickel present in pea root nodule cytoplasm fraction (Cacho et al., 2010).…”

Section: Introductionmentioning

confidence: 99%

Update of the risk assessment of nickel in food and drinking water

Schrenk¹,

Bignami²,

Bodin³

et al. 2020

EFS2

View full text Add to dashboard Cite

The European Commission asked EFSA to update its previous Opinion on nickel in food and drinking water, taking into account new occurrence data, the updated benchmark dose (BMD) Guidance and newly available scientific information. More than 47,000 analytical results on the occurrence of nickel were used for calculating chronic and acute dietary exposure. An increased incidence of postimplantation loss in rats was identified as the critical effect for the risk characterisation of chronic oral exposure and a BMDL 10 of 1.3 mg Ni/kg body weight (bw) per day was selected as the reference point for the establishment of a tolerable daily intake (TDI) of 13 lg/kg bw. Eczematous flare-up reactions in the skin elicited in nickel-sensitised humans, a condition known as systemic contact dermatitis, was identified as the critical effect for the risk characterisation of acute oral exposure. A BMDL could not be derived, and therefore, the lowest-observed-adverse-effect-level of 4.3 lg Ni/kg bw was selected as the reference point. The margin of exposure (MOE) approach was applied and an MOE of 30 or higher was considered as being indicative of a low health concern. The mean lower bound (LB)/upper bound (UB) chronic dietary exposure was below or at the level of the TDI. The 95th percentile LB/UB chronic dietary exposure was below the TDI in adolescents and in all adult age groups, but generally exceeded the TDI in toddlers and in other children, as well as in infants in some surveys. This may raise a health concern in these young age groups. The MOE values for the mean UB acute dietary exposure and for the 95th percentile UB raises a health concern for nickel-sensitised individuals. The MOE values for an acute scenario regarding consumption of a glass of water on an empty stomach do not raise a health concern.

show abstract

Section: Introductionmentioning

confidence: 99%

Update of the risk assessment of nickel in food and drinking water

Schrenk¹,

Bignami²,

Bodin³

et al. 2020

EFS2

View full text Add to dashboard Cite

show abstract

“…The salts formed from these organic acids with heavy metals enter the plants. So, Ni-gluconate and Ni-citrate complexes were found to be present in the cocoa (Peeters et al, 2017). The potential of organic acids producing PGPR was highlighted in review (Rajkumar et al, 2012); however there is a controversial study, which did not show significant effect on the mobilization of HM (Evangelou, Ebel & Schaeffer, 2006;Park et al, 2011).…”

Section: Bacterial Defense Systems and Pgpr Mediated Plant Defense Strategiesmentioning

confidence: 99%

Nickel stress-tolerance in plant-bacterial associations

Pishchik

Mirskaya

Chizhevskaya

et al. 2021

PeerJ

View full text Add to dashboard Cite

Nickel (Ni) is an essential element for plant growth and is a constituent of several metalloenzymes, such as urease, Ni-Fe hydrogenase, Ni-superoxide dismutase. However, in high concentrations, Ni is toxic and hazardous to plants, humans and animals. High levels of Ni inhibit plant germination, reduce chlorophyll content, and cause osmotic imbalance and oxidative stress. Sustainable plant-bacterial native associations are formed under Ni-stress, such as Ni hyperaccumulator plants and rhizobacteria showed tolerance to high levels of Ni. Both partners (plants and bacteria) are capable to reduce the Ni toxicity and developed different mechanisms and strategies which they manifest in plant-bacterial associations. In addition to physical barriers, such as plants cell walls, thick cuticles and trichomes, which reduce the elevated levels of Ni entrance, plants are mitigating the Ni toxicity using their own antioxidant defense mechanisms including enzymes and other antioxidants. Bacteria in its turn effectively protect plants from Ni stress and can be used in phytoremediation. PGPR (plant growth promotion rhizobacteria) possess various mechanisms of biological protection of plants at both whole population and single cell levels. In this review, we highlighted the current understanding of the bacterial induced protective mechanisms in plant-bacterial associations under Ni stress.

show abstract

“…4 In general, the nickel content in foodstuffs is considered to be lower than 0.2 mg kg -1 , oatmeal (1 mg kg -1 ), roasted cashew (up to 5 mg kg -1 ), cocoa (up to 12 mg kg -1 ), chocolate (up to 6 mg kg -1 ) soy products (2 -6 mg kg -1 ), legumes (2 mg kg -1 ), almonds (0.8 mg kg -1 ), black tea (up to 3 mg kg -1 ) can be given as examples for nickelrich food sources. 4,5 The nickel concentration in drinking water is generally found to be less than 10 μg L -1 . The average intake of nickel is around 7.5 and 15.0 μg for adults who drink 1.5 L water per day.…”

Section: Introductionmentioning

confidence: 99%

Separation and Preconcentration of Nickel(II) from Drinking, Spring, and Lake Water Samples with Amberlite CG-120 Resin and Determination by Flame Atomic Absorption Spectrometry

et al. 2018

View full text Add to dashboard Cite

In this study, Amberlite CG-120 adsorbent was used for the separation/preconcentration of Ni(II) ions in commercial drinking, spring and lake water samples before detection by flame atomic absorption spectrometry. Various optimization parameters for Ni(II) determination, such as pH, eluent type and concentration, sample and eluent flow rates, amount of adsorbent, were investigated to obtain better sensitivity, accuracy, precision and quantitative recovery. Furthermore, the interference effects of some ions on the recovery efficiency of Ni(II) were also investigated. The optimum experimental parameters were obtained in the case of pH 1; 5 mL of 4 mol L-1 HCl for eluent and 0.3 g for the adsorbent amount. The limit of detection was found to be 0.58 μg L-1 and linearity ranged from 5 to 50 μg L-1. The accuracy of the method was tested by the certified reference material of TMDA-70.2 Ontario Lake Water at a 95% confidence level.

show abstract

Nickel speciation in cocoa infusions using monolithic chromatography – Post-column ID-ICP-MS and Q-TOF-MS

Cited by 24 publications

References 25 publications

Update of the risk assessment of nickel in food and drinking water

Update of the risk assessment of nickel in food and drinking water

Nickel stress-tolerance in plant-bacterial associations

Separation and Preconcentration of Nickel(II) from Drinking, Spring, and Lake Water Samples with Amberlite CG-120 Resin and Determination by Flame Atomic Absorption Spectrometry

Contact Info

Product

Resources

About