Resistance exercise and testosterone treatment alters the proportion of numerical density of capillaries of the left ventricle of aging Wistar rats

Abstract

Resistance exercise combined with testosterone triggered a response of compensatory adjustment in the increase of Nv [cap], collagen and interstitial space, increasing perfusion and nutrition to the heart.

Effects of testosterone administration on liver structure and function in aging rats

“…However, supraphysiologic doses of testosterone have been suggested to improve muscle strength and different metabolic parameters in shorter time [10][11][12]. On the other hand, these exacerbated doses could injure the liver [9,13,14], as well as, other organs as heart and prostate [6,9,15].…”

Testosterone and Voluntary Exercise, Alone or Together Increase Cardiac Activation of AKT and ERK1/2 in Diabetic Rats

“…42 It is also reported that, when exercise is added to testosterone supplementation, cardiac remodeling process, as structural or biochemical changes, becomes more efficient. 43 Regarding the limitations of this study and results of previous studies, we did not measure circulating testosterone after castration.…”

Effects of resistance training on liver structure and function of aged rats

“…The height of the equipment (ladder) is 110 cm (43.3 inches) with an inclination angle of 80 . The top of the equipment had a plastic box for the accommodation of the animals in the interval between sets [11,12].…”

“…Over the course of 16 weeks, the amount of weight carried by each rat was equivalent to 50% of its body weight (BW). The BW was measured at the beginning of each week of the experiment and the new weight to be carried by the animals during that week was adjusted according to their BW [11,12]. No external stimulus was necessary so that the animals conduct the training.…”