Die Bedeutung des Diabetes mellitus für das Glaukom

Klemm, M.; Gesser, C.

doi:10.1055/s-0033-1360143

Cited by 10 publications

(5 citation statements)

References 26 publications

(38 reference statements)

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“…Most of these conditions are related to elevated intraocular pressure (IOP), which can also damage the optic nerve directly [ 10 ]. However, given that at least some glaucoma patients have low or normal intraocular pressure, other systemic conditions, such as diabetes, cardiovascular disease, and obesity, may also be relevant [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Association between Glaucoma and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Systematic Review

Shi

Guan

et al. 2015

PLoS ONE

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BackgroundObstructive sleep apnea syndrome (OSAS) is a common disease that increases the risk of diabetes, heart disease, and stroke. However, studies of an association between OSAS and glaucoma neuropathy have reported controversial findings.ObjectiveThe main purpose of this study was to evaluate whether a significant association exists between OSAS and glaucoma by performing a meta-analysis of previous studies.MethodsA comprehensive literature search using the PubMed and Embase databases was performed to identify cross-sectional, case-control, and cohort studies related to the topic. We estimated a pooled odds ratio (OR) for the association between OSAS and glaucoma, by a fixed- or random-effects model.ResultsIn total, 16 studies with 2,278,832 participants met the inclusion criteria: one retrospective cohort study reported an adjusted hazard ratio of glaucoma of 1.67 (95% CI = 1.30–2.17). Using a fixed-effects model, the pooled OR of six case-control studies was 1.96 (95% CI = 1.37 2.80). A significant association was also identified in a meta-analysis of nine cross-sectional studies using a random-effects model, which showed a pooled OR of 1.41 (95% CI = 1.11 1.79). However, the reported pooled estimates for case control studies and cross-sectional studies were based on unadjusted ORs.ConclusionsOur results suggest that OSAS is associated with the prevalence of glaucoma. However, this result was based only on unadjusted estimates. Prospective cohort studies designed to take into consideration potential confounders, or examination of data from interventional trials to determine whether a reduction in OSAS status is associated with a reduced incidence of glaucoma, are needed to clarify whether OSAS is an independent risk factor for glaucoma.

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Section: Introductionmentioning

confidence: 99%

Association between Glaucoma and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Systematic Review

Shi

Guan

et al. 2015

PLoS ONE

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“…suggest that Puerto Rico patients between 40 to 79 years of age with diabetic retinopathy have an increased risk of developing open-angle glaucoma with each subsequent decade ( 8 ). Klemm M, Gesser C. In his article communicated that Primary open angle glaucoma is more frequent than neovascular glaucoma, but neovascular glaucoma is very aggressive and difficult to treated ( 6 , 8 ). Applying the test of refraction chances (odds ratio) found that subjects with DM type 1 have a 5.94 times greater chance of developing secondary glaucoma, but is of primary (P <0.0001).…”

Section: Discussionmentioning

confidence: 99%

“…Despite this, the main reason for neovascular glaucoma in diabetes is proven to be retinal ischemia due to diabetic vessel damage. Primary open angle glaucoma is more frequent than neovascular glaucoma, but neovascular glaucoma is very aggressive and difficult to treat ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Influence of Type of Diabetes Mellitus on the Development and Type of Glaucoma

Halilovic

Ljaljević

Alimanovic

et al. 2015

Med Arh

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Aim:Main the goal of the research is to analyze the occurrence of glaucoma in patients with diabetes mellitus type 1 (DM type 1) and diabetes mellitus type 2 (DM type 2).Patients and methods:The study involved 140 patients, 34 with DM type 1 and 106 with DM type2. In relation to the type of glaucoma to the patients are divided into two groups: Primary and Secondary glaucoma. According to the stage of diabetic retinopathy (DR) patients were analyzed in three groups: non-proliferative, preproliferative and proliferative DR. Since ophthalmological parameters were analyzed: best corrected visual acuity (BCVA), intraocular pressure (IOP), visual field (VF) of computerized perimetry, excavatio optic nerve (E/D) by optic coherent tomography (OCT).Results:Applying the test of quotient chance found that subjects with DM type 1 have a 5.94 times greater chance of developing secondary glaucoma, but is of primary (P <0.0001). In patients with DM type 2, where the chance of getting the subjects of secondary glaucoma 4.43 times larger than that of the primary (P = 0.0002).Conclusion:Patients with DM type have great chance of developing secondary glaucoma of the primary. Primary glaucoma more common in NPDR but secondary glaucoma more common in PDR.

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“…Glaucoma and cataract were noted in 8.3% and 15% of a diabetic in our study. Primary open angle glaucoma and neovascular glaucoma are associated to diabetes mellitus and DR.[ 21 22 ] The risk of lens opacity also is higher among persons with diabetes. [ 23 ] Control of risk factors reduces progression of both DR as well as lens opacities in diabetics.…”

Section: Discussionmentioning

confidence: 99%

Magnitude and determinants of diabetic retinopathy among persons with diabetes registered at employee health department of a tertiary Eye Hospital of central Saudi Arabia

Khandekar¹,

Hassan²,

Dhibi³

et al. 2015

Oman J Ophthalmol

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Background:To estimate the magnitude and determinants of diabetic retinopathy (DR) among persons with diabetes registered at the employee health department of King Khaled Eye Specialist Hospital (KKESH).Methods:A retrospective review of medical records was conducted in 2013–14 at KKESH. The case record review extracted demographic, profile of diabetes, diabetic complications, and different blood indices to determine the status of potential risk factors. Ocular profile, especially DR was also noted.Results:Our cohort had 94 staff with diabetes. Eye examination was carried out in 51 (54.8%) of them. The rate of DR was 52% (95% confidence interval (CI) 28–66). Sight-threatening diabetic retinopathy (STDR) (proliferative DR and/or diabetic macular edema) was present in 40% of those examined. Good glycemic control was noted in 42% of participants. Duration of diabetes was associated with DR (P = 0.04). Good glycemic control was negatively associated to DR (odds ratio = 0.2 [95% CI 0.04–0.6]). The coverage of eye screening was 55% only. Laser treatment was given to 80% of STDR cases. The lens opacity and glaucoma rate was 15% and 8.3%, respectively.Conclusions:Low coverage for eye screening and laser treatment to diabetics among the staff of an eye hospital is a matter of concern. The underlying causes of low coverage of screening, digital fundus photography as a screening tool and management should be addressed.

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Die Bedeutung des Diabetes mellitus für das Glaukom

Cited by 10 publications

References 26 publications

Association between Glaucoma and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Systematic Review

Association between Glaucoma and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Systematic Review

Analysis of the Influence of Type of Diabetes Mellitus on the Development and Type of Glaucoma

Magnitude and determinants of diabetic retinopathy among persons with diabetes registered at employee health department of a tertiary Eye Hospital of central Saudi Arabia

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