Characterization, Antioxidant and Antibacterial Potentials of Tamarindus indica L. Fruit Pulp Extract Loaded O/W Nanoemulsions

Songkro, Sarunyoo; Isnaini, Nadia; Sungkharak, S; Tanmanee, Niwan; Maneenuan, Duangkhae; Kaewnopparat, Nattha

doi:10.1590/s2175-97902022e19373

Cited by 2 publications

(1 citation statement)

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“…The FTIR spectra of DTGS and the spectra of the excipients were compared. DTGS peak loss or peak fluctuation in each spectrum was taken into account [36].…”

Section: Fourier Transform Infrared Spectroscopy (Ftir)mentioning

confidence: 99%

Formulation and Evaluation of Dolutegravir Sodium Nanoemulsion for the Treatment of HIV

Rodriques¹,

Prajapati²

2022

Pharmacophore

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The purpose of this research was to develop and evaluate the Nanoemulsion of Dolutegravir sodium. Nanoemulsion was made by the high-shear homogenization method. Materials and method: Oleic acid was used as the oil phase, Tween 80, and Acconon MC8-2 EP/NF (Smix; 1:1) were utilized as surfactant and co-surfactant respectively while distilled water was employed as an aqueous phase. The formulations were evaluated based on globule size, zeta potential, pH, viscosity, percentage transmittance, centrifugation, dye test, dilutability test, and Fourier transform spectroscopy. Furthermore, in vitro drug release studies and stability studies were also conducted. NE1 has shown the least particle size of 96.71 nm, viscosity of 86.4 cp, and maximum drug release of 97.55 % CDR in 45 hrs compared with pure drug (32.98% CDR in 45 hrs). The stability study confirmed no changes in formulations at 1 month at 40 0 ± 2 0 C and 75% ± 5%. The findings suggest that nanoemulsions might be an effective vehicle for the oral administration of Dolutegravir sodium for the treatment of HIV.

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“…The FTIR spectra of DTGS and the spectra of the excipients were compared. DTGS peak loss or peak fluctuation in each spectrum was taken into account [36].…”

Section: Fourier Transform Infrared Spectroscopy (Ftir)mentioning

confidence: 99%