Disseminated cutaneous sporotrichosis associated with ocular lesion in an immunocompetent patient

Medeiros, Karina Bittencourt; Landeiro, Luana Gomes; Diniz, Lúcia Martins; Falqueto, Aloísio

doi:10.1590/abd1806-4841.20164859

Cited by 14 publications

(14 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only two patients (1.2%) developed extracutaneous sporotrichosis: one with osteoarticular involvement (disseminated infection) and the other with ocular mucosa involvement (disseminated infection). 23 The lower and upper limbs were mostly affected by the disease (157 cases, 92%), as shown in Figure 5, whereas the hand (45 cases, 26.3%) was the initial inoculation point of the etiological agent (Table 3). Lesion biopsies were performed in 60 (35%) patients, followed by open wound swab in 38 (22.2%) and aspiration of cutaneous nodule secretion in 37 (21.6%).…”

Section: Resultsmentioning

confidence: 99%

“…Some of these cases were partially described in previous publications. [20][21][22][23] The majority of the patients were male (80.7%, 4:1 male-to-female ratio); most patients were Caucasian (86.5%), and showed an age range from 6 to 77 years. Only six patients (3.5%) were younger than 12 years old ( Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…[14][15][16] In the local context, the largest sporotrichosis case series have been reported in Southern and Southeastern Brazil, the main endemic areas of the disease. [17][18][19] There is little sporotrichosis-related information in the state of Espírito Santo, [20][21][22][23] also located within southeastern Brazil. In this way, our findings could be used in the state health surveillance program, for understanding and comparing the actual disease epidemiological changing pattern in the country.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiological and Clinical Aspects of Sporotrichosis in Espírito Santo State, Southeast Brazil: A Study of Three Decades (1982–2012)

Caus

Zanotti

Faccini-Martínez

et al. 2019

The American Journal of Tropical Medicine and Hygiene

Self Cite

View full text Add to dashboard Cite

This study discusses a historical patient series and is designed to describe clinical and epidemiological characteristics of human sporotrichosis in the state of Espírito Santo, Brazil. Data were derived from patients treated at the Infectious Diseases service of Cassiano Antônio Moraes University Hospital in Vitória, the state capital, from July 1982 to June 2012. A total of 171 patients were diagnosed with sporotrichosis, mostly men (80.7%) with a median age of 33 years and 5 months. We can presume an approximate average incidence rate of 4.9 cases per 100,000 inhabitants during the studied period. All the patients were involved in occupational or leisure activities with direct contact with soil or plants. Most cases were recorded in the mountainous region of the state during the hot and rainy periods. The average time elapsed from lesion progression to diagnosis was 3 months, with the lymphocutaneous form being the most common (70.2%), followed by the fixed cutaneous form (28.6%). Diagnosis was confirmed in 93.6% of the cases by culturing Sporothrix spp. in Sabouraud dextrose agar, and from the clinical features in the remaining cases. Aspiration of cutaneous nodule secretions was the best method for the collection of clinical specimens for disease diagnosis. A 25% saturated solution of potassium iodide (SSKI) was provided to almost all patients (98.8%), with therapeutic success. In conclusion, in this retrospective study in the state of Espírito Santo, we found that sporotrichosis affects primarily the ³ 10-year-old population, and the most common presentation is the lymphocutaneous form affecting the lower and upper limbs, and the infection appeared to be acquired predominantly through occupational activities. Treatment with SSKI was safe and effective.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiological and Clinical Aspects of Sporotrichosis in Espírito Santo State, Southeast Brazil: A Study of Three Decades (1982–2012)

Caus

Zanotti

Faccini-Martínez

et al. 2019

The American Journal of Tropical Medicine and Hygiene

Self Cite

View full text Add to dashboard Cite

show abstract

“…Droplets from sick cats, whose secretions contain large amounts of fungi, are known to reach human membranes without the need of a local lesion for inoculation. 2 , 3 Interestingly, both patients were children, the age group that maintains intimate contact with domestic animals, often taking them close to the face, thus favoring fungal inoculation on the face and ocular mucosa.…”

Section: Discussionmentioning

confidence: 99%

Ocular involvement in sporotrichosis: report of two cases in children

Lemes

Veasey

Mayor

et al. 2021

Anais Brasileiros de Dermatologia

View full text Add to dashboard Cite

Sporotrichosis is a subcutaneous mycosis that affects humans and animals, with a typically subacute or chronic evolution, caused by Sporothrix spp ., a dimorphic fungus. Although the cutaneous form is the most frequent presentation, the ocular involvement has been more frequently diagnosed in endemic areas, affecting mainly children and the elderly. Approximately 80% of affected patients have the lymphocutaneous form, while only 2.3% have conjunctival lesions, with 0.7% showing primary ocular involvement. We describe two cases of sporotrichosis with ocular involvement in children through inoculation by felines, with a good response to antifungal treatment.

show abstract

“…The infection usually reaches the deeper skin layers through implantation of the fungus caused by minor local trauma or animal bites and scratches and more commonly affects outdoor workers 2,3 . The lymphocutaneous form of the disease has the highest incidence, followed by the fixed cutaneous form [4][5][6] . The disseminated cutaneous form is rare and usually affects immunosuppressed individuals 2,5 .…”

Section: Introductionmentioning

confidence: 99%

Case series of sporotrichosis at a teaching hospital in Brazil

Benvegnú

Dallazzem

Chemello

et al. 2020

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Sporotrichosis is a subcutaneous fungal infection with a worldwide distribution and higher incidence in tropical and subtropical areas, such as the Brazilian territory, where it has been standing out due to its frequent epidemics. Thus, the present study aimed to evaluate the prevalence of sporotrichosis and profile the affected patients at a university teaching hospital in the central region of Rio Grande do Sul, Brazil. Methods: This study was a case series of patients diagnosed with Sporothrix spp. from January 2006 to December 2015 by microscopic examination or fungal isolates. Medical records were reviewed for epidemiological data. Results: Forty-three cases of sporotrichosis were diagnosed through the period. The sample comprised predominantly young male adults and rural workers. The most common disease type was lymphocutaneous (51%), followed by fixed cutaneous form (32.5%). The predominant location was the upper limbs (70%), followed by the lower limbs (16%). A significant association was observed between the lymphocutaneous form and upper limb location and between the fixed cutaneous form and lower limb location (p = 0.019). Potassium iodine and itraconazole were the most common treatments. Conclusions: This study will help update the epidemiological situation of sporotrichosis in the central region of the state of Rio Grande do Sul, Brazil, over the last decade.

show abstract

Disseminated cutaneous sporotrichosis associated with ocular lesion in an immunocompetent patient

Cited by 14 publications

References 5 publications

Epidemiological and Clinical Aspects of Sporotrichosis in Espírito Santo State, Southeast Brazil: A Study of Three Decades (1982–2012)

Epidemiological and Clinical Aspects of Sporotrichosis in Espírito Santo State, Southeast Brazil: A Study of Three Decades (1982–2012)

Ocular involvement in sporotrichosis: report of two cases in children

Case series of sporotrichosis at a teaching hospital in Brazil

Contact Info

Product

Resources

About