A 59-year-old female patient, previously healthy, immunocompetent, presented left
bulbar conjunctiva lesions and nodular-ulcerated lesions on the arms and
cervical region, besides left cervical and retroauricular lymphadenopathy. She
had previous contact with domestic cats that excoriated her face. The diagnosis
was conclusive of disseminated sporotrichosis through clinical and
epidemiological history and cultures of skin and ocular secretions. It evolved
with good response to oral antifungal therapy.
Bacillary angiomatosis is an infection determined by Bartonella
henselae and B. quintana, rare and prevalent in
patients with acquired immunodeficiency syndrome. We describe a case of a
patient with AIDS and TCD4+ cells equal to 9/mm3, showing
reddish-violet papular and nodular lesions, disseminated over the skin, most on
the back of the right hand and third finger, with osteolysis of the distal
phalanx observed by radiography. The findings of vascular proliferation with
presence of bacilli, on the histopathological examination of the skin and bone
lesions, led to the diagnosis of bacillary angiomatosis. Corroborating the
literature, in the present case the infection affected a young man (29 years
old) with advanced immunosuppression and clinical and histological lesions
compatible with the diagnosis.
Angiosarcoma is a rare and aggressive tumor with high rates of metastasis and
relapse. It shows a particular predilection for the skin and superficial soft
tissues. We report three distinct and typical cases of angiosarcoma that were
diagnosed in a single dermatology clinic over the course of less than a year: i)
Angiosarcoma in lower limb affected by chronic lymphedema, featuring
Stewart-Treves syndrome; ii) a case of the most common type of angiosarcoma
loated in the scalp and face of elderly man and; iii) a skin Angiosarcoma in
previously irradiated breast. All lesions presented characteristic
histopathological findings: irregular vascular proliferation that dissects the
collagen bundles with atypical endothelial nuclei projection toward the
lumen.
Histiocytoid Sweet's Syndrome is a rare inflammatory disease described in 2005 as
a variant of the classical Sweet's Syndrome (SS). Histopathologically, the
dermal inflammatory infiltrate is composed mainly of mononuclear cells that have
a histiocytic appearance and represent immature myeloid cells. We describe a
case of Histiocytoid Sweet's Syndrome in an 18-year-old man. Although this
patient had clinical manifestations compatible with SS, the cutaneous lesions
consisted of erythematous annular plaques, which are not typical for this entity
and have not been described in histiocytic form so far. The histiocytic subtype
was confirmed by histopathological analysis that showed positivity for
myeloperoxidase in multiple cells with histiocytic appearance.
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