Sexual Function in Male Patients with Metabolic Syndrome and Effective Parameters on Erectile Dysfunction

Görgel, Sacit Nuri; Gorgel, Ahmet; Şefik, Ertuğrul

doi:10.1590/s1677-5538.ibju.2014.01.08

Cited by 20 publications

(12 citation statements)

References 32 publications

(30 reference statements)

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“…Gorgel et al conducted a study to investigate the relationship between metabolic syndrome and sexual function and effective parameters on erectile dysfunction (ED), and concluded that metabolic syndrome (including type 2 diabetes), smoking and obesity are potential risk factors for lack of sexual drive and satisfaction and ED [14].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Sexual Frequency in Married Egyptians with Type 2 Diabetes Mellitus

Gadalla¹

2016

Andrology (Los Angel)

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Background and objective: Sexual health is an important, however a neglected factor in patients with diabetes. Effects of diabetes mellitus (e.g. erectile dysfunction) and implication on sexual frequency and function among men with diabetes have not been well investigated. The current study aims to evaluate the sexual frequency, sexual function and their association with type 2 diabetes compared to that in an age-matched control group.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Sexual Frequency in Married Egyptians with Type 2 Diabetes Mellitus

Gadalla¹

2016

Andrology (Los Angel)

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“…It is intuitive that the presence of a greater amount of periprostatic adipose tissue may increase the chance of injury to the neurovascular bundle. Obesity is also associated with the metabolic syndrome, the use of medications that may affect the quality of the erection, in addition to an endothelial inflammation and dysfunction (27). In the series of Wiltz et al the results were significantly worse after RARP for obese patients when compared to overweight (BMI≥25kgm 2 and <30kgm 2 ) and normal patients (BMI<25kgm 2 ), with 48.4%, 59.6% and 68.5% of potent patients after 12 months, and 55.9%, 78.9% and 80.3% after 24 months, respectively (p=0.02) (13).…”

Section: Discussionmentioning

confidence: 99%

Factors affecting urinary continence and sexual potency recovery after robotic-assisted radical prostatectomy

et al. 2019

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Introduction Robot-assisted radical prostatectomy (RARP) is the most recent surgical technique for localized prostate cancer. The Da Vinci (Intuitive Surgical, Sunnyvale, CA) system was first introduced in Brazil in 2008, with a fast growing number of surgeries performed each year.Objective Our primary endpoint is to analyze possible predictors of functional outcomes, related to patient and tumor features. As secondary endpoint, describe functional outcomes (urinary continence and sexual potency) from RARP performed in the Sírio-Libanês Hospital (SLH), a private institution, in São Paulo, from April 2008 to December 2015.Materials and Method Data from 104 consecutive patients operated by two surgeons from the SLH (MA and SA) between 2008 and 2015, with a minimum 12 months follow-up, were collected. Patient features (age, body mass index - BMI, PSA, date of surgery and sexual function), tumor features (tumor stage, Gleason and surgical margins) and follow-up data (time to reach urinary continence and sexual potency) were the variables collected at 1, 3, 6 and 12 month and every 6 months thereafter. Continence was defined as the use of no pad on medical interview and sexual potency defined as the capability for vaginal penetration with or without fosphodiesterase type 5 inhibitors.Results Mean age was 60 years old and mean BMI was 28.45 kg/m2. BMI >30kg/m2 (p<0.001) and age (p=0.011) were significant predictors for worse sexual potency after surgery. After 1, 3, 6 and 12 months, 20.7%, 45.7%, 60.9% and 71.8% from patients were potent, respectively. The urinary continence was reached in 36.5%, 80.3%, 88.6% and 92.8% after 1, 3, 6 and 12 months, respectively. Until the end of the study, only one patient was incontinent and 20.7% were impotent.Conclusion Age was a predictor of urinary and erectile function recovery in 12 months. BMI was significant factor for potency recovery. We obtained in a private hospital good functional results after 12 months of follow-up.

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“…A leptin/adiponektin arány eltolódása tüneteket nem okozó gyulladásos állapotot vált ki, amely IR-val és endothelfunkció-zavarral társul [13,29]. Megfigyelték, hogy a túlsúlyos és elhízott betegeknél a szexuális zavar gyakoribb, mint a soványakban, és a testtömegindex (BMI) növekedésével a zavar fokozódik [30,31]. Ennek hátterében neurobiológiai, hormonális, vascularis és mentális zavar állhat.…”

Section: Elhízásunclassified

“…Mivel a pénisz artériája vékonyabb a koszorúereknél, a szisztémás érkárosodás korábban vezet EDhoz, mint más CV betegséghez [38]. Az ED, a CV betegségek és a MS rizikótényezői megegyeznek egymással, és a MS komponensei közül a hasi elhízás látszik az ED fő kockázati tényezőjének [31]. Megfigyelték, hogy a MS kezelésével emelkedik a tesztoszteronszint, csökken az IR, és csökken az ED mértéke is [39].…”

Section: Férfiakban Előforduló Szexuális Funkciózavarunclassified

A szexuális funkciózavar és a metabolikus szindróma kapcsolata

2019

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The prevalence of the metabolic syndrome, type 2 diabetes mellitus, cardiovascular diseases, obesity and depression have increased during the recent years. As the sexual dysfunction is also frequent, we aimed to search for the associations between sexual dysfunction and the metabolic syndrome and its components, respectively, by reviewing the literature. The clinical and biochemical components of the metabolic syndrome included cardiovascular disease, type 2 diabetes mellitus, visceral obesity and depression, furthermore, insulin resistance, atherogenic lipid profile, hypogonadism, chronic systemic inflammation and endothelial dysfunction were all demonstrated to affect adversely the sexual function. The dysfunction of the sexual arousal response shows a strong association in men and a milder one in women with the cardiovascular diseases and depression. Sexual function in diabetes mellitus is mostly impaired by microvascular injury, polyneuropathy and autonomic neuropathy. Erectile dysfunction and disorder of the female sexual arousal response and the orgasm, respectively, are associated with insulin resistance, atherogenic lipid profile and systemic inflammatory condition in overweight or obese patients. Sexual dysfunction particularly in men can be an early sign of the severe complications of metabolic syndrome. The pathogenetic link between the metabolic syndrome and the sexual dysfunction seems to be the insulin resistance. Both metabolic syndrome and sexual dysfunction can be restored by altering the lifestyle. Orv Hetil. 2019; 160(3): 98–103.

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Sexual Function in Male Patients with Metabolic Syndrome and Effective Parameters on Erectile Dysfunction

Abstract: ARTICLE INFO

Cited by 20 publications

References 32 publications

Evaluation of Sexual Frequency in Married Egyptians with Type 2 Diabetes Mellitus

Evaluation of Sexual Frequency in Married Egyptians with Type 2 Diabetes Mellitus

Factors affecting urinary continence and sexual potency recovery after robotic-assisted radical prostatectomy

A szexuális funkciózavar és a metabolikus szindróma kapcsolata

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