Sociodemographic profile of medicines users in Brazil: results from the 2014 PNAUM survey

Bertoldi, Andréa Dâmaso; Pizzol, Tatiane da Silva Dal; Ramos, Luiz Roberto; Mengue, Sotero Serrate; Luiza, Vera Lúcia; Tavares, Noêmia Urruth Leão; Farías, Mareni Rocha; Oliveira, Maria Auxiliadora; Arrais, Paulo Sérgio Dourado

doi:10.1590/s1518-8787.2016050006119

Cited by 32 publications

(39 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although women represent the main group affected by DRPs, as demonstrated in this study and in others conducted in Brazil 4, [14][15][16]18,23 , the trend towards an increase in the proportion of male cases may be related to the higher consumption of these products by men in the last decade 16,27,28 compared to previous decades 29,30 .…”

Section: Discussionsupporting

confidence: 47%

Tendências de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas

Mathias

Guidoni

Girotto

2019

Rev. bras. epidemiol.

View full text Add to dashboard Cite

RESUMO: Introdução: Os eventos toxicológicos relacionados a medicamentos têm alto impacto na morbimortalidade, representando a primeira causa de intoxicação no Brasil. Objetivo: Descrever as tendências de casos de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas. Método: Estudo com abordagem quantitativa (transversal e de tendência), com análise dos dados referentes aos casos de eventos toxicológicos relacionados a medicamentos atendidos pelo Centro de Informações Toxicológicas do Hospital Universitário da Universidade Estadual de Londrina. Os dados foram coletados das fichas de atendimento, referentes ao período de 1985 a 2014. Para a análise estatística, utilizou-se um modelo de regressão linear simples. Resultados: Dos 36.707 casos atendidos pelo serviço, 22,5% (n = 8.608) foram eventos toxicológicos relacionados a medicamentos. Houve um aumento da proporção de casos em ambos os sexos (R2 = 0,195; p = 0,014) e no sexo masculino (R2 = 0,403; p < 0,001). Detectou-se tendência de elevação da proporção de casos envolvendo a classe de analgésicos, anti-inflamatórios e imunossupressores (R2 = 0,521; p = 0,018), antidepressivos (R2 = 0,923; p < 001) e antipsicóticos (R2 = 0,869; p < 0,001). Os antimicrobianos apresentaram tendência de redução da proporção de casos (R2 = 0,773; p = 0,001). Conclusões: Observou-se tendência de aumento da proporção de casos de eventos toxicológicos relacionados a medicamentos no sexo masculino. Também houve aumento nas tendências envolvendo analgésicos/anti-inflamatórios/imunossupressores, antidepressivos e antipsicóticos.

show abstract

Section: Discussionsupporting

confidence: 47%

Tendências de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas

Mathias

Guidoni

Girotto

2019

Rev. bras. epidemiol.

View full text Add to dashboard Cite

show abstract

“…The factors that may explain this phenomenon include pharmacokinetic, pharmacodynamic, and body-weight when compared to men, besides hormonal factors 6,21 . Women present more health problems, which are less serious on average, but they use health services more, have more appointments and tests, obtain more diagnoses and medical prescriptions, and thus consume more medicines, prescribed or not 15,22,23 . Another factor that may have contributed to this gender difference was the fact that ADEs were also reported by users of contraceptives in the study.…”

Section: Discussionmentioning

confidence: 99%

Prevalência e características dos eventos adversos a medicamentos no Brasil

et al. 2018

Self Cite

View full text Add to dashboard Cite

The aim of this study was to describe the prevalence of adverse drug events (ADEs) and associated factors reported by users of medicines in Brazil. This was a cross-sectional population-based study conducted from September 2013 to February 2014 with data from the Brazilian National Survey on Access, Use, and Promotion of Rational Use of Medicines (PNAUM). The study included all individuals that reported the use of medicines and identified, among them, all those reporting at least one problem with the medicine's use. A descriptive analysis was performed to estimate ADE prevalence and 95% confidence intervals (95%CI) among the target variables. Crude and adjusted prevalence ratios were calculated using Poisson regression to investigate factors associated with ADEs. Overall ADE prevalence in Brazil was 6.6% (95%CI: 5.89-7.41), and after multivariate analysis, higher prevalence was associated with female gender, residence in the Central and Northeast regions, consumption of more medicines, "bad" self-rated health, and self-medication. The drugs most frequently reported with ADEs were fluoxetine, diclofenac, and amitriptyline. The most frequent ADEs were somnolence, epigastric pain, and nausea. Most reported ADEs were mild, avoidable, and associated with medicines used frequently by the population. The study provided knowledge on the size of the problem with use of medicines in Brazil.

show abstract

“…1,2 Pharmacies in England dispensed more than one million prescriptions in 2016 and approximately four million were dispensed in the United States. [5][6][7][8] Through clinical pharmacy services, community pharmacists play an important role in promoting the rational use of medicines and improving the health of patients. [5][6][7][8] Through clinical pharmacy services, community pharmacists play an important role in promoting the rational use of medicines and improving the health of patients.…”

Section: What Is K Nown and Objec Tivementioning

confidence: 99%

“…In the academic brainstorming session, the researchers had a mean age of 28.66 ± 5.82 (24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40) years and a mean professional experience of 4.76 ± 2.38 (2)(3)(4)(5)(6)(7)(8) years. Their discussion was based on the importance of the instrument items for dispensing.…”

Section: Academic Brainstormingmentioning

confidence: 99%

“…3,4 In Latin American countries, the prevalence of the use of medicines is high in all age groups and in several therapeutic categories. [5][6][7][8] Through clinical pharmacy services, community pharmacists play an important role in promoting the rational use of medicines and improving the health of patients. [9][10][11] These services, which include the dispensing of medicines, can be defined as the counselling given to the patient about the dispensed medicines and how to use them.…”

Section: What Is K Nown and Objec Tivementioning

confidence: 99%

See 1 more Smart Citation

Development and content validation of an instrument to document the dispensing of prescribed medicines

et al. 2019

View full text Add to dashboard Cite

Summary What is known and objective Qualified dispensing is fundamental for the promotion of the rational use of medicines. Documentation is an indicator of quality and one of the essential steps in the care process. However, in Brazil, there are no models of clinical documentation applicable to dispensing practices. Thus, the objective of this study was to develop and validate an instrument to document the dispensing process of prescribed medicines. Methods A methodological development study was carried out from February 2017 to October 2017 in two stages, which were (i) the development of the instrument and (ii) content validation of the proposed instrument. The development phase comprised three stages, which were (i) the elaboration of the prototype based on a previously performed systematic review, (ii) academic brainstorming and (iii) a pre‐Delphi consensus. The content validation process was performed using the Delphi technique. The instrument was sent to 40 experts with experience in dispensing, and the consensus among them was calculated using the content validity index (CVI). The study was approved by the Ethics Committee, and all participants signed an informed consent document detailing the terms of the study. Results In the development stage, three versions of the instrument were generated, which were the prototype, version 1 (changed after academic brainstorming) and version 2 (changed after the pre‐Delphi). In the content validation process of version 2 of the instrument, 23 experts returned their evaluation in the first round of the Delphi process and 17 in the second. All the items obtained a CVI >0.83, which resulted in the validation of the instrument. The final instrument comprised the following sections: general information, the identification of technical and legal problems of prescriptions, the conduct for the resolution of the technical and legal problems of prescriptions, medication dispensed, suspected drug‐related problems, verbal guidance, written guidance, referral and the referral result. What is new and conclusion The developed and validated instrument presents the main variables that should be documented during the dispensing process.

show abstract

Sociodemographic profile of medicines users in Brazil: results from the 2014 PNAUM survey

Cited by 32 publications

References 23 publications

Tendências de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas

Tendências de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas

Prevalência e características dos eventos adversos a medicamentos no Brasil

Development and content validation of an instrument to document the dispensing of prescribed medicines

Contact Info

Product

Resources

About