“…In general, vaccine efficacy highly depends on the dose and strains of the vaccine and challenge viruses, as well as, the route of administration, the appropriate vaccination time, and the levels of maternal antibodies (OIE, 2012). Inspite of extensive control measures the farmers are still facing the problems of Gumboro even in the vaccinated flocks (Hasan et al, 1998;Dias et al, 2009). Control of IBD poses one of the most challenging tasks in the poultry health management.…”