2009
DOI: 10.1590/s1516-89132009000600008
|View full text |Cite
|
Sign up to set email alerts
|

Effect of an aqueous extract of annatto (Bixa orellana) seeds on lipid profile and biochemical markers of renal and hepatic function in hipercholesterolemic rats

Abstract: Annatto extract is a natural food color obtained from the outer coatings of the seeds of the Annatto tree (Bixa orellana L.). This is the first report in

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2

Citation Types

2
11
0
1

Year Published

2012
2012
2022
2022

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 19 publications
(14 citation statements)
references
References 27 publications
2
11
0
1
Order By: Relevance
“…Plates D: Photomicrographs of liver sections showing fatty changes after 28 days of oral administration of2500mg/kg body weight of aqueous extract (8)and fatty changes with vacuolationat 2500 mg/kg body weight of ethanolic extract (9) of Triplochiton scleroxylon. Hematoxylin and eosin stain.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Plates D: Photomicrographs of liver sections showing fatty changes after 28 days of oral administration of2500mg/kg body weight of aqueous extract (8)and fatty changes with vacuolationat 2500 mg/kg body weight of ethanolic extract (9) of Triplochiton scleroxylon. Hematoxylin and eosin stain.…”
Section: Resultsmentioning
confidence: 99%
“…Increase in the activities of alkaline phosphatase (Tables 1 and 2), γ-glutamyltransferase (Tables 3 and 4) and alanine amino transaminase (Tables 5 and 6) obtained in this study must have been due to leakages from the liver as a result of damage on it caused by higher doses of both aqueous and ethanolic extracts of Triplochiton scleroxylon. Elevation in the activities of liver biomarkers in the plasma is often useful as an index of liver damage (Paula et al, 2009) …”
Section: Discussionmentioning
confidence: 99%
“…Hepatotoxicity of annatto extract was discarded by Bautista et al (2004) and Garcia et al (2012); however, Paula et al (2009) reported that the addition of aqueous extract of annatto seed to rat diet caused liver hypertrophy. Thus, it can be inferred that the excess of atypical carotenoids present in diets with increasing levels of annatto contributed to the increased liver weight, since this organ is where lipids are metabolized.…”
Section: Resultsmentioning
confidence: 99%
“…where rats fed a high-cholesterol diet along with aqueous extract of annatto seeds had their levels of total cholesterol and LDL decreased and increase in the levels of HDL (Paula et al, 2009). …”
Section: Discussionmentioning
confidence: 99%