2007
DOI: 10.1590/s1516-89132007000300018
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Bacteriocins from lactic acid bacteria: purification, properties and use as biopreservatives

Abstract: Biopreservation systems in foods are of increasing interest for industry and consumers. Bacteriocinogenic lactic acid bacteria and/or their isolated bacteriocins are considered safe additives (GRAS),

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Cited by 262 publications
(182 citation statements)
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“…isolated from foods like dairy and meat products, these antimicrobial substances have been consumed for a long time (23). Several bacteriocins from Gram-positive bacteria are very effective, have wide inhibitory spectra and may be used as antimicrobial agents in various practical applications (9,34).…”
Section: Introductionmentioning
confidence: 99%
“…isolated from foods like dairy and meat products, these antimicrobial substances have been consumed for a long time (23). Several bacteriocins from Gram-positive bacteria are very effective, have wide inhibitory spectra and may be used as antimicrobial agents in various practical applications (9,34).…”
Section: Introductionmentioning
confidence: 99%
“…Lactobacilli have great potential for antimicrobial production such as bacteriocins. L. acidophilus has been reported for the production of acidocin and lactacin B and F (Parada et al, 2007). L. fermentum, isolated from the gastrointestinal digestive tract and mucosa in the swine and poultry have been described as potential probiotic organisms and inhibitors of enteric pathogens of these animals, especially against E. coli, Salmonella spp., Shigella sonnei, and with less efficiency, enterotoxigenic Staphylococcus aureus (Lin et al, 2007).…”
Section: Resultsmentioning
confidence: 99%
“…In this context, the lactic acid bacteria appear as an interesting alternative for this application due to their flexibility for use as a probiotic organism, by the use of cells to adhesion, colonization and organic acids production in the intestinal tract, and also for the synthesis of low molecular weight peptides with bactericidal or bacteriostatic effects -the bacteriocins (Parada et al, 2007;Lin et al, 2007). The aim of this study was to investigate the potential of isolates belonging to the strains bank of the Bioprocess Engineering and Biotechnology Department at Universidade Federal do Paraná (UFPR, Brazil) to produce antimicrobial compounds capable of inhibiting the Gramnegative pathogen growth isolated from the animal faeces, and finally, perform a study on their antimicrobial substance production.…”
Section: Introductionmentioning
confidence: 99%
“…According to Stevens et al, antibiotics have a bactericidal effect against Gram-positive bacteria by inducing the formation of porous bacterial cytoplasmic membranes and inhibiting the biosynthesis of the cell wall by binding with the molecular precursor cell walls and lipid II, which is located in the peptidoglycan [11]. Gram-negative bacteria such as A. actinomycetemcomitans are generally insensitive to lantibiotics, because the outer membrane of the Gram-negative bacteria which serves as a permeability barrier prevents the entry of macromolecules such as lantibiotic cells [9].…”
Section: Discussionmentioning
confidence: 99%