Frequency of congenital craniofacial malformations in a Brazilian Reference Center

Abstract

OBJECTIVE: To evaluate the frequency of craniofacial anomalies in patients treated at a Brazilian Reference Center for craniofacial deformities. METHOD: Retrospective epidemiological study evaluating the clinical records of 1,142 patients: 656 (57.4%) male and 486 (42.6%) female, between 1992 and 2008. RESULTS: Among birth defects, non-syndromic cleft lip and/or palate were the most frequent ones (778 cases; 68.1%), followed by single or multiple congenital anomalies without cleft lip and/or palate (240 cases; 21%), recognized syndromes or sequences (56 cases; 5%), syndromes with orofacial cleft as a component (41 cases; 3.5%), and orofacial clefts in association with systemic malformations (27 cases; 2.4%). CONCLUSIONS: Non-syndromic cleft lip and/or palate was the congenital defect most frequently identified, although, isolated anomalies and syndromes involving craniofacial structures were quite frequent. Furthermore, the need for studies to identify the frequency and risk factors associated with craniofacial anomalies in the Brazilian population is emphasized in order to plan comprehensive strategies and integrated actions for the development of preventive programs and treatment.

Nursing workload in specialized Semi-intensive Therapy unit: workforce size criteria

“…The cleft lip and palate malformations do not represent most common syndromic cleft lip and/or palate craniofacial involvement, involving aesthetic, functional and psychosocial problems (8) . The functional problems are internalized when they are associated with genetic syndromes and/or clinics, including respiratory and food problems in most cases.…”

Vídeo educativo: estratégia de treinamento para cuidadores de crianças com fissura labiopalatina

“…The literature shows a prevalence of cleft lip and lip-palate in males, whereas cleft palate is prevalent in females. (1) The mean age was 10 months. The optimal age for a cheiloplasty and palatoplasty is no consensus; however, good results, especially regarding the quality of speech, have been evidenced in cases in which surgical correction occurred before 12 months of age.…”

“…(1,2) The rehabilitation process of patients with cleft lip and palate begins with the primary plastic surgeries named cheiloplasty and palatoplasty, which are performed in the first months and years of life, respectively. Cheiloplasty is the reconstructive surgery of the cleft lip, and palatoplasty is the reconstruction of the cleft palate.…”

Care to children with cleft lip-palate: an integrative review

“…A mong the developmental anomalies, cleft lip-palate (CLP) is one of the most common craniofacial malformations. 1 The prevalence varies according to geographical location. In Brazil, the occurrence of an affected child is every 650 live births.…”

“…6 Studies show higher occurrence of CLP then by CL and CP. 1,6 According to some studies, more than half of affected children are male and most common type in this genre is CLP.…”