Vitamina A e diabetes gestacional

Lira, Larissa Queiroz de; Dimenstein, Roberto

doi:10.1590/s0104-42302010000300023

Cited by 20 publications

(11 citation statements)

References 35 publications

(67 reference statements)

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“…VAD is more frequent in the last quarter of pregnancy because of the physiological increase in maternal blood volume and accelerated fetal development in the final phase of pregnancy [41,42]. Pregnant women may be more prone to developing VAD during periods in which there is a shortage of foods rich in vitamin A or in the presence of infections, diabetes mellitus, or gestational diabetes [43,44,45].…”

Section: Vitamin a Deficiency During Pregnancy: Epidemiological Asmentioning

confidence: 99%

“…Maternal VAD is possibly one of the main causes of fetal growth restriction and of the subsequent risk of insulin resistance and glucose intolerance in adulthood [94,95]. Studies suggest that VAD is associated with diabetes mellitus and gestational diabetes [45]. VAD during pregnancy can affect the development of the endocrine pancreas in rats [95], suggesting a possible role of VAD in the pathogenesis of diabetes [96].…”

Section: Vitamin a And Pregnancy: Importance And Effects Of Deficimentioning

confidence: 99%

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Vitamin A and Pregnancy: A Narrative Review

et al. 2019

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Vitamin A is a crucial micronutrient for pregnant women and their fetuses. In addition to being essential for morphological and functional development and for ocular integrity, vitamin A exerts systemic effects on several fetal organs and on the fetal skeleton. Vitamin A requirements during pregnancy are therefore greater. Vitamin A deficiency (VAD) remains the leading cause of preventable blindness in the world. VAD in pregnant women is a public health issue in most developing countries. In contrast, in some developed countries, excessive vitamin A intake during pregnancy can be a concern since, when in excess, this micronutrient may exert teratogenic effects in the first 60 days following conception. Routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and mortality is not recommended; however, in regions where VAD is a public health issue, vitamin A supplementation is recommended to prevent night blindness. Given the importance of this topic and the lack of a complete, up-to-date review on vitamin A and pregnancy, an extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data.

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Section: Vitamin a Deficiency During Pregnancy: Epidemiological Asmentioning

confidence: 99%

Section: Vitamin a And Pregnancy: Importance And Effects Of Deficimentioning

confidence: 99%

Vitamin A and Pregnancy: A Narrative Review

et al. 2019

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“…According to Lira and Dimenstein (2010), concerning the knowledge about the relevant physiological roles of Vitamin A and the factors that influence its concentrations, the need of monitoring this vitamin during pregnancy is clear, especially if accompanied by diabetes mellitus, in order to prevent installation of other pathological complications for the mother and her infant.…”

Section: Introductionmentioning

confidence: 99%

Gestational diabetes: a risk of puerperal hypovitaminosis A?

Resende

Lira

Grilo

et al. 2015

An. Acad. Bras. Ciênc.

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The influence of gestational diabetes on vitamin A deficiency in lactating women and, consequently, in their newborn has been verified through a cross-sectional case-control study conducted with volunteer puerperal women. The control group consisted of healthy women and the test group was composed of women with gestational diabetes. One hundred and seven women were recruited, corresponding to 71 controls and 36 cases. Personal, gestational and newborn data were collected directly from medical records during hospitalization. The retinol was determined in maternal colostrum and serum by High Performance Liquid Chromatography. Postpartum women with gestational diabetes were older, had more children and a higher prevalence of cesarean delivery. No difference was found in retinol concentration in maternal milk and serum between the groups. However, it was observed that 16.7% had vitamin A deficiency in the group of patients with diabetes and only 4.1% had such deficiency in the control group. Although no difference was found in colostrum and serum retinol concentration between women with and without gestational diabetes, the individual analysis shows that those with diabetes are at higher risk of being vitamin A deficient.

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“…Gestational diabetes mellitus can also be predicted by VA, as shown via plasma RBP concentrations ( 88–90 ). One review concluded that the presence of gestational diabetes can diminish the effectiveness of antenatal VAS, and that the altered metabolic state can cause increases in VA intake to lead to hepatic toxicity ( 91 ). Among diabetic pregnancies, the adipokine RBP does not have a statistically significant association with the occurrence of PE ( 92 ).…”

Section: Resultsmentioning

confidence: 99%

Vitamin A Requirements in Pregnancy and Lactation

Gannon

Jones

Mehta

2020

Current Developments in Nutrition

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Pregnancy and lactation are critical life stages with unique nutritional requirements, including for vitamin A (VA). Current Dietary Reference Intakes (DRIs) for VA were published in 2001. The objective of this review was to identify and categorize evidence related to VA requirements in pregnancy and lactation since these DRIs were formulated. We searched MEDLINE and included articles according to an analytic framework of maternal VA exposure on status and health outcomes in the mother-child dyad. Intermediate and indirect evidence supports that maternal VA intakes can impact the mother's VA status, breastmilk, and health outcomes, as well as the child's VA status and select health outcomes. Food-based approaches may lead to more sustained, sufficient VA status in mothers and children. Research needs include further study linking maternal VA intakes on maternal and child VA status, and further associations with outcomes to determine intake requirements to optimize health.

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Vitamina A e diabetes gestacional

Cited by 20 publications

References 35 publications

Vitamin A and Pregnancy: A Narrative Review

Vitamin A and Pregnancy: A Narrative Review

Gestational diabetes: a risk of puerperal hypovitaminosis A?

Vitamin A Requirements in Pregnancy and Lactation

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