Emprego de membrana de quitosana em feridas cutâneas induzidas experimentalmente em equinos

Martins, Edivaldo Aparecido Nunes; Invernizzi, Mariana Sachi; Campos, Maria Gabriela Nogueira; Teodoro, Piter Aparecido; Contieri, Marcelo Bittencourt; Silva, Luís Cláudio Lopes Correia da

doi:10.1590/s0103-84782013001000015

Cited by 9 publications

(7 citation statements)

References 11 publications

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“…Any interference resulting from the systemic application of anti-inflammatory phenylbutazone would occur both in the control and treated wounds. OLIVEIRA JR. et al (2012) and MARTINS et al (2013) also used phenylbutazone during the postoperative period in studies evaluating skin healing in the equine species.…”

Section: Resultsmentioning

confidence: 99%

“…In both groups, there was a gradual reduction in the wound areas from the 7 th DPO. COELHO et al, (1999) and MARTINS et al (2013) also observed an increase in the areas of the wounds in the initial phase of the healing process, caused by the shrinkage of the rim of the lesions due to the action of the lines of tension (Langer Lines). In making the square wounds, the skin was incised in both directions, longitudinal and transversal, determining the increase in area due to stretching caused by the transverse incisions according to Langer's lines (ALGOWER, 1977apud COELHO et al, 1999.…”

Section: Lucas Et Almentioning

confidence: 94%

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Copaiba oil in experimental wound healing in horses

et al. 2017

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The aim of this study was to evaluate the effects of 10% copaiba oil in experimentally induced wounds in horses. Four wounds were made in the lumbar and metacarpal regions of eight adult horses. In the treatment group, the wounds received 10% copaiba oil and in the control group 0.9% sodium chloride, in the daily dressing for 21 days. The wounds were evaluated three, 7, 14, and 21 days postoperatively. No significant differences were observed between the groups. The mean lumbar wound contraction rates were 80.54% and 69.64%, for the control and treated groups, respectively. For the wounds in the metacarpal region, these averages were 44.15% and 52.48%, respectively. Under the experimental conditions of the present study, it is concluded that 10% copaiba oil has beneficial in wound healing in the equine species and suggest that copaiba oil can be used as a therapeutic possibility in equine wound therapy.

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Section: Resultsmentioning

confidence: 99%

Section: Lucas Et Almentioning

confidence: 94%

Copaiba oil in experimental wound healing in horses

et al. 2017

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“…A widely number of materials has been explored to this application. Different sources has been used, such as metallic, ceramic and polymerics [4,5].…”

Section: Drug Delivery Systemsmentioning

confidence: 99%

Characterization and Microbiological Application of Ciprofloxacin Loaded in Natural Rubber Latex Membranes

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et al. 2017

BJPR

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Natural rubber latex (NRL) from Hevea brasiliensis presents interesting characteristics in biomedical research due to its ability to stimulate angiogenesis, cellular adhesion and formation of extracellular matrix. A broad spectrum antibacterial agent used in skin infection is Ciprofloxacin hydrochloride (CIP). It is a fluoroquinolone employed to treat different bacterial infections caused by gram-positive and gram-negative microorganism. The aim of the present study is to promove Original Research Article

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“…Martins, et al [191] investigated chitosan utilization in experimentally induced skin wounds in horses, and found that the chitosan membrane accentuated granulation tissue formation, emphasizing a potential repairing effect. Chitosan (CS)-based hydrogels are biocompatible, and in terms of wound healing, can afford a humid environment, offer security against secondary infections, eliminate wound exudate, incite quickly healing, and form soft scars [192].…”

Section: Chitosan In Wound Healingmentioning

confidence: 99%

A Review on Chitosan’s Uses as Biomaterial: Tissue Engineering, Drug Delivery Systems and Cancer Treatment

et al. 2020

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Chitosan, derived from chitin, is a biopolymer consisting of arbitrarily distributed β-(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine that exhibits outstanding properties— biocompatibility, biodegradability, non-toxicity, antibacterial activity, the capacity to form films, and chelating of metal ions. Most of these peculiar properties are attributed to the presence of free protonable amino groups along the chitosan backbone, which also gives it solubility in acidic conditions. Moreover, this biopolymer can also be physically modified, thereby presenting a variety of forms to be developed. Consequently, this polysaccharide is used in various fields, such as tissue engineering, drug delivery systems, and cancer treatment. In this sense, this review aims to gather the state-of-the-art concerning this polysaccharide when used as a biomaterial, providing information about its characteristics, chemical modifications, and applications. We present the most relevant and new information about this polysaccharide-based biomaterial’s applications in distinct fields and also the ability of chitosan and its various derivatives to selectively permeate through the cancer cell membranes and exhibit anticancer activity, and the possibility of adding several therapeutic metal ions as a strategy to improve the therapeutic potential of this polymer.

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Emprego de membrana de quitosana em feridas cutâneas induzidas experimentalmente em equinos

Abstract: RESUMO O objetivo deste estudo foi avaliar os efeitos da membrana (fi lme) de quitosana no processo de reparação de feridas cutâneas distais em equinos. Foram induzidas feridas cutâneas nas regiões metacarpianas

Cited by 9 publications

References 11 publications

Copaiba oil in experimental wound healing in horses

Copaiba oil in experimental wound healing in horses

Characterization and Microbiological Application of Ciprofloxacin Loaded in Natural Rubber Latex Membranes

A Review on Chitosan’s Uses as Biomaterial: Tissue Engineering, Drug Delivery Systems and Cancer Treatment

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