In the world, on process of petroleum refining industries, several catastrophic accidents occur constantly, resulting from processing with highly toxic substances, which ends up causing environmental impacts and destroying lives. The explosion, is the type of increased accident that most causes immediate deaths, leading companies to pay damages and rebuild their destroyed assets again. So, the objective of this work is to demonstrate the use of virtual simulations to identify and quantify the possible effects of physical effects and explosion damages, resulting from the Petroleum Refining process operation of the diesel hydrotreatment unit, Abreu e Lima Refinery (ALR or RNEST in Brazil, country of Latin American), a city located in northeastern Brazil. Simulations were performed with the Aloha software in three pipes of the ALR. The XXXVII ENCONTRO NACIONAL DE ENGENHARIA DE PRODUCAO "A Engenharia de Produção e as novas tecnologias produtivas: indústria 4.0, manufatura aditiva e outras abordagens avançadas de produção"