Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba

Tilaoui, Mounir; Mouse, Hassan Aît; Jaafari, Abdeslam; Aboufatima, Rachida; Chait, Abderrahman; Zyad, Abdelmajid

doi:10.1590/s0102-695x2011005000114

Cited by 37 publications

(20 citation statements)

References 18 publications

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“…Similarly, Dahmani-Hamzaoui and Baaliouamer [39] identified the davanon in the essential oil of sagebrush Djelfa. Tilaoui et al [40] showed that the oil sagebrush of Imilchil ErRachidia (Morocco) contains the verbenol as major compound. The eucalyptol is identified as the major constituent in the essential sagebrush oil from southern Spain (41% maximum) [37] and Egypt [41].…”

Section: Resultsmentioning

confidence: 99%

Essential Oil Composition and Antimicrobial Activity of Artemisia herba– alba Asso Grown in Algeria

Lakehal¹,

Meliani²,

Benmimoune³

et al. 2016

Med chem (Los Angeles)

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In the recent decades, antimicrobial plant products have gained special interest because of the resistance to antibiotics that some microorganisms have acquired. Aromatic and medicinal plants are an important source of bioactive molecules, especially in volatile extracts, that are considered among the most important antimicrobial agents present in these plants. Volatile components of Artemisia herba-alba Asso essential oil obtained by hydrodistillation growing in Algeria (Djelfacityof south Algeria) were investigated by GC/FID and GC-MS. The major components were found to be camphor (39.5%), chrysanthenone (10.38%), 1,8-cineole (8.6%), α-thujone (7.03%), Borneol (3.35%) and bornyl acetate (2.52%). The essential oil has been tested for antimicrobial activity against Gram-negative and Gram-positive bacteria. Inhibition of growth was tested by the agar diffusion method. The Minimal Inhibitory Concentration (MIC) was determined by the method of agar dilution.

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Section: Resultsmentioning

confidence: 99%

Essential Oil Composition and Antimicrobial Activity of Artemisia herba– alba Asso Grown in Algeria

Lakehal¹,

Meliani²,

Benmimoune³

et al. 2016

Med chem (Los Angeles)

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“…Essential oils of A. absinthium which contained higher amounts of trans-sabinyl acetate and cis/trans-thujones exhibited more toxicity on brine shrimp (Judzentiene et al, 2012). Moreover, the essential oils of A. capillaris and A. herbaalba are regarded as good candidates for further study, because they showed significant anti-proliferative activity against the human oral cancer and acute lymphoblastic leukaemia (CEM) cell lines respectively (Cha et al, 2009;Tilaoui et al, 2011). Dichloromethane extracts of A. annua exhibited higher cytotoxicity in comparison with methanol extracts against HeLa cancer cells (Efferth et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Cytotoxic and Apoptotic Effects of Extracts of Artemisia ciniformis Krasch. & Popov ex Poljakov on K562 and HL-60 Cell Lines

Tayarani‐Najaran

Hajian²,

Mojarrab³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Asian Pac J Cancer Prev, 15 (17), [7055][7056][7057][7058][7059] IntroductionIncrease in prevalence of cancer cases has been associated with the expansion of industrial, chemical and radioactive pollutants, also the gap between human being and nature (Colditz and Wei, 2012; Fasinu and Orisakwe, 2013). Despite the progress in the field of medicinal chemistry and development in the synthesis of several new therapeutic compounds, the role of plants and phytochemicals can not be ignored in pharmaceutical sciences (Cerella et al., 2014). Due to the presence of compounds with cytotoxic and anti-tumor activity in some plants and significant efficacy of plant derived compounds in inhibition and treatment of cancer, as well as the amazing diversity of natural compounds in plants, researches to find new phytochemicals and to evaluate their biological effects is essential and a research priority (Tayarani-Najaran et al., 2011;Wegiera et al., 2012;Sehitoglu et al., 2014).Artemisia is a genus belonging to the family Asteraceae Compositae with commonly fragrant species. Some species such as A. dracunculus L. are kitchen plants and used for

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“…It should be noted that in Artemisia species, artemisinin is not the unique medicinal molecule. The genus is abundant with other sesquiterpene lactones (de Almeida et al, ; Ivanescu, Miron, & Corciova, ; Shoaib et al, ; Tilaoui et al, ), which could have antihelmintic effects with less mammalian toxicity risk (Kerboeuf, Riou, & Guégnard, ).…”

Section: Pharmacological Properties Of Artemisininmentioning

confidence: 99%

More insights into the pharmacological effects of artemisinin

Zyad

Tilaoui

Jaafari

et al. 2017

Phytotherapy Research

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Artemisinin is one of the most widely prescribed drugs against malaria and has recently received increased attention because of its other potential biological effects. The aim of this review is to summarize recent discoveries of the pharmaceutical effects of artemisinin in basic science along with its mechanistic action, as well as the intriguing results of recent clinical studies, with a focus on its antitumor activity. Scientific evidence indicates that artemisinin exerts its biological activity by generating reactive oxygen species that damage the DNA, mitochondrial depolarization, and cell death. In the present article review, scientific evidence suggests that artemisinin is a potential therapeutic agent for various diseases. Thus, this review is expected to encourage interested scientists to conduct further preclinical and clinical studies to evaluate these biological activities.

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Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba

Cited by 37 publications

References 18 publications

Essential Oil Composition and Antimicrobial Activity of Artemisia herba– alba Asso Grown in Algeria

Essential Oil Composition and Antimicrobial Activity of Artemisia herba– alba Asso Grown in Algeria

Cytotoxic and Apoptotic Effects of Extracts of Artemisia ciniformis Krasch. & Popov ex Poljakov on K562 and HL-60 Cell Lines

More insights into the pharmacological effects of artemisinin

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