Antimicrobial activity of Byrsonima species (Malpighiaceae)

Michelin, D. C.; Sannomiya, Míriam; Figueiredo, Maria E.; Rinaldo, Daniel; Santos, Lourdes Campaner dos; Souza‐Brito, Alba Regina Monteiro; Vilegas, Wagner; Salgado, Hérida Regina Nunes

doi:10.1590/s0102-695x2008000500009

Cited by 18 publications

(10 citation statements)

References 26 publications

(27 reference statements)

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“…Furthermore, ethnopharmacological studies have demonstrated the popular use of Byrsonima plants for the treatment of diarrhea, fever, asthma, and skin infections (Guilhon-Simplicio and Pereira 2011). Research has confirmed the biological activities of these plants, especially with respect to topical and systemic anti-inflammatory activity (Maldini et al 2009;Moreira et al 2011), antioxidant (Pereira et al 2015 and antimicrobial activities (Michelin et al 2008). Lima et al (2008) and Santos et al (2012), studying, respectively, B. fagifolia and B. intermedia extracts, observed gastroprotective and antidiarrheal activities, supporting the traditional use of this genus to treat gastrointestinal disorders.…”

Section: Introductionmentioning

confidence: 78%

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds

et al. 2016

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Brazilian flora biodiversity has been widely investigated to identify effective and safe phytotherapeutic compounds. Among the investigated plant species, the Byrsonima genus exhibits promising biological activities. This study aimed at evaluating the cytotoxicity of B. correifolia, B. verbascifolia, B. fagifolia and B. intermedia extracts using different assays in two cell lines (primary gastric and HepG2 cells). The different extract concentrations effects on cell viability were assayed using the MTT, aquabluer, neutral red and LDH assays. Non-cytotoxic concentrations were selected to generate cell proliferation curves and to assess cell cycle kinetics by flow cytometry. Byrsonima extracts differentially affected cell viability depending on the metabolic cellular state and the biological parameter evaluated. B. fagifolia and B. intermedia extracts exhibited lower cytotoxic effects than B. correifolia and B. verbascifolia in all assays. The results obtained with LDH and flow cytometry assays were more reliable, suggesting that they can be useful in the screening for herbal medicine and to further characterize these extracts as phytotherapeutic compounds.

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Section: Introductionmentioning

confidence: 78%

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds

et al. 2016

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“…Pesquisas de atividade antimicrobiana utilizando extratos de plantas populares apresentam cada vez maior importância contra microrganismos patogênicos como Candida albicans, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus e Staphylococcus epidermidis (Pessini et al, 2003;Pereira et al, 2004;Aguiar et al, 2008;Coutinho et al, 2008;Michelin et al, 2008;Salvagnini et al, 2008;Bertucci et al, 2009;Silva Junior et al, 2009). Uma destas plantas é a Ilex paraguariensis A.…”

Section: Introductionunclassified

Atividade antimicrobiana dos extratos de folhas e ramos da Ilex paraguariensis A. St.-Hil., Aquifoliaceae

Biasi¹,

Grazziotin²,

Hofmann³

2009

Rev. bras. farmacogn.

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"Antimicrobial activity of extracts of the leaves and branches of Ilex paraguariensis (erva-mate)". For the evaluation of the antimicrobial activity of Ilex paraguariensis six microorganisms were used: Candida albicans, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis. In disks of filter paper 10 µl of hydro-alcoholic extracts of the leaves and branches from two distinct environments were added, with and without sun exposure. The extracts have inhibited levedura, gram-negative bacillus and gram-positive cocos, with no activity to Escherichia coli.

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“…Since catechins have hydroxyl groups available for hydrogen bond formation, their extraction with polar solvents is facilitated (Marques et al, 2016). In opposition to the identification of catechins in Byrsonima species' (Malpighiaceae) leaves (Michelin et al, 2008), this study was not able to find them in L. lactescens leaves (Table 1). A plausible explanation is that different genera may have different phytochemical compositions.…”

Section: Discussionmentioning

confidence: 73%

<b>Phytochemistry and antibacterial activity of aqueous and hydroalcoholic extracts of three medicinal plants against food pathogens

Santos

Silva

et al. 2018

Acta Sci. Biol. Sci.

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This study aimed to characterize the phytochemical compositions of three medicinal Brazilian plants' leaves and bast extracts, and to determine their antibacterial activity on three foodborne and waterborne bacterial pathogens. Parkia platycephala, Pouteria ramiflora and Lophanthera lactescens leaves and basts were collected and aqueous and hydroalcoholic extracts were prepared. Qualitative screening of the phytochemical extracts was performed with three replicates and in triplicate in order to identify the bioactive compounds. The Minimal Inhibitory Concentration and Minimal Bactericide Concentration were determined by microdilution in broth and Escherichia coli, Salmonella typhimurium and Staphylococcus aureus growth was observed on agar plates. Phytochemical composition analysis allowed for the identification of anthraquinones, catechins, saponins, tannins, sesquiterpenlactones and other lactones in the three plants' leaves and bast aqueous and hydroalcoholic extracts. Eighty-three percent of the plant extracts showed antibacterial activity against S. aureus, and P. platycephala extracts were the only ones that inhibited E. coli and S. typhimurium growth. The present study contributes significantly to the phytochemical composition characterization of three plant species commonly used in Brazilian traditional medicine. The plant extracts' in vitro antibacterial activity was demonstrated and catechins present in the extracts are, most likely, the bioactive compounds responsible for this action.

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Antimicrobial activity of Byrsonima species (Malpighiaceae)

Cited by 18 publications

References 26 publications

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds

Atividade antimicrobiana dos extratos de folhas e ramos da Ilex paraguariensis A. St.-Hil., Aquifoliaceae

<b>Phytochemistry and antibacterial activity of aqueous and hydroalcoholic extracts of three medicinal plants against food pathogens

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