Efeitos de óleos essenciais de plantas no tempo de sono induzido por cetamina em camundongos

Fauth, Simony; Campos, Adriana Rolim; Silveira, Edilberto R.; Rao, V. S. N.

doi:10.1590/s0102-695x2002000300052

Cited by 6 publications

(5 citation statements)

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“…Data published by other authors reinforce the pharmacological potential of araçá leaves and fruits (FAUTH et al, 2002;MEDINA et al, 2011;VOSS-RECH et al, 2011;CORRÊA et al, 2011;OLIVEIRA et al, 2012;PATEL, 2012).…”

Section: Introductionsupporting

confidence: 69%

Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves

Durães¹,

Clementino²,

Fari³

et al. 2017

Biosci. J.

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Psidium myrsinites DC. is species known as "araçá", from the Cerrado (savanna) biome in Brazil. It is commonly used as a medicinal plant in the treatment of diarrhea because of its astringent properties. The aims of this study were to carry out phytochemical screening with an exploratory purpose; to investigate toxicity by brine shrimp (Artemia salina) lethality bioassay; and to evaluate antimicrobial activity against Gram-positive and Gram-negative bacteria by determining the minimum inhibitory concentration of the essential oil, acetonic and ethanolic crude extracts, and the fractions obtained with organic solvents of Psidium myrsinites DC. leaves. The phytochemical profile determined the major classes of secondary metabolites present as phenolic compounds (tannins, coumarins, flavonoids, anthraquinone glycosides and terpene compounds). The essential oil and hexane fraction demonstrated a level of strong and mild toxicity respectively, thus encouraging further research with isolated substances from them. The crude ethanolic and acetonic extracts, and hexane fractions, chloroform intermediary, ethyl acetate and aqueous fraction from crude acetonic extract showed the best inhibitory effect on bacterial growth of Gram-positive bacteria with minimum inhibitory concentrations ranging between 62.5 and 250 µg.mL -1 . However, the presence of secondary compounds such as tannins, flavonoids and terpenes is probably associated with the inhibitory effect on tested microorganisms, which could justify the medicinal use of the leaves of this species.

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Section: Introductionsupporting

confidence: 69%

Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves

Durães¹,

Clementino²,

Fari³

et al. 2017

Biosci. J.

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“…However, this chemical composition is sensibly dependent on the geographic location and the phenology of the plant material harvested (Durán, Monsalve, Martínez, & Stashenko, 2007), which has categorized L. alba in seven chemotypes (Table 1; Linde et al, 2016). Essential oils from chemotypes I and III plants present antispasmodic (Viana, Vale, Silva, & Matos, 2000;Blanco et al, 2013;Sousa et al, 2015;Silva et al, 2018;Carvalho et al, 2018), anticonvulsive (Fauth, Campos, Silveira, & Rao, 2002;Maynard et al, 2011), anxiolytic (Hatano,Torricelli,Giassi,Coslope,Fig. 1.…”

Section: Biological Activity Of L Alba Essential Oilsmentioning

confidence: 99%

“…& Viana, 2012;Junior et al, 2018), and antiinflammatory effects (Sepúlveda-Arias, Veloza, Escobar, Orozco, & Lopera, 2013). On contact with the skin, they are not irritating nor alter the histopathology (Neira et al, 2018), and are sleep enhancers (Fauth et al, 2002), anesthetic, and sedative (Salbego et al, 2017a). They also have antioxidant activity, although in this property the collection site is quite determining, given that chemotype I was a good antioxidant, while other chemotype III specimens had moderate and absent effect (Stashenko, Jaramillo, & Martínez, 2004;Olivero-Verbel, González-Cervera et al, 2010).…”

Section: Biological Activity Of L Alba Essential Oilsmentioning

confidence: 99%

Essential oils biological activity of the Lippia alba (Verbenaceae) shrub

Ortega-Cuadros

Guevara

Castillo

et al. 2020

RBT

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Introduction: Lippia alba is an aromatic species belonging to the Verbenaceae family. Its essential oils have been used in different industries, because of its biological properties. Objective: Identify the perspectives of the biotechnological applications of Lippia alba essential oils. Methodology: A scoping review was conducted on the biological activity of Lippia alba essential oils registered until October, 2018 in EBSCO, Embase, Scopus, and Lilacs databases. Results: Chemotypes I and III have been reported for different biological activities from the evaluations performed on microorganisms, fish, arthropods, small mammals, and cell lines; fundamentally associated with antibacterial, antifungal, cytotoxic, antioxidant, and sedative effects, among others. Records focused mainly on the health, fishing industry, and agrifood sectors. Conclusion: Studies on the effect of essential oil are promising, but do not reflect a continuity of the research toward prototypes or finished commercial products. Research groups must unify evaluation methodologies and include in all studies the relationship between phytochemical and biological activity for the meta-analyses to be possible. Likewise, they must join efforts through the National System for Agricultural Innovation (SNIA, for the term in Spanish) to generate finished products that impact upon society and facilitate progress in the country’s bio-economy.

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“…Few pharmacological studies have been done on the genus Lippia. Among these, the studies on the species Lippia multifl ora, Lippia origanoides, Lippia sidoides, L. integrifolia, Lippia lacunosa, Lippia rotundifolia and Lippia alba (Pascual et al, 2001, Fauth et al, 2002Oliveira et al, 2006;Leitão et al, 2006;Barbosa-Filho et al, 2006) are included. The essential oil of Lippia alba showed antimicrobial activity against gram positive microorganisms, in general, with minimum inhibitory concentration (MIC) between 0.31-0.63 mg/mL (Alea et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial activity and phytochemical profile from the roots of Lippia alba (Mill.) N.E. Brown

Filho¹,

Melo²,

Saraiva³

et al. 2006

Rev. bras. farmacogn.

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RESUMO: "Atividade antimicrobiana e perfi l fi toquímico das raízes de Lippia alba (Mill.) N.E. Brown". Lippia alba (Mill.) N.E. Brown (Verbenaceae) é geralmente usada na medicina popular brasileira para o tratamento de doenças gástricas, febre, asma e como tranqüilizante. Este trabalho avaliou a atividade antimicrobiana dos extratos acetato de etila, metanol e aquoso das raízes de L. alba usando métodos de difusão em poços e o perfi l fi toquímico. Os resultados obtidos mostraram que os extratos acetato de etila e metanol apresentaram atividade antimicrobiana contra Staphylococcus aureus (ATCC 6538P), Staphylococcus aureus (ATCC 6538) e Klebsiella pneumonia (ATCC 10031). Terpenóides, fenilpropanóides e açúcares foram detectados na análise fi toquímica.Unitermos: Lippia alba, Verbenaceae, atividade antimicrobiana, análise fi toquímica.ABSTRACT: Lippia alba (Mill.) N.E. Brown (Verbenaceae) is commonly used in the Brazilian folk medicine to the treatment of gastric illnesses, diarrhea, fever, asthma, and as a tranquilizer. This work evaluated the antimicrobial activity of ethyl acetate, methanol and aqueous extracts from the roots of the L. alba using plates-holes diffusion assay and the phytochemical profi le. The results obtained showed that the ethyl acetate and methanol extracts presented antimicrobial activity against Staphylococcus aureus (ATCC 6538P), Staphylococcus aureus (ATCC 6538) and Klebsiella pneumonia (ATCC 10031). Terpenoids, phenylpropanoids and sugars were detected in the phytochemical analysis.

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Efeitos de óleos essenciais de plantas no tempo de sono induzido por cetamina em camundongos

Cited by 6 publications

References 0 publications

Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves

Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves

Essential oils biological activity of the Lippia alba (Verbenaceae) shrub

Antimicrobial activity and phytochemical profile from the roots of Lippia alba (Mill.) N.E. Brown

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