Estudo botânico, fitoquímico e avaliação da atividade antimicrobiana de Rubus rosaefolius Sm. - Rosaceae

Abstract

Rubus rosaefolius Sm., Rosaceae, is a shrub with compound leaves, recurvate prickles, white flowers and aggregate fruit, popularly known as sylvan strawberry. The present research concerns its botany (macroscopic and microscopic studies), phytochemistry and antimicrobial properties. The presence of antraquinones, saponins, flavonoids, alkaloids and tannins on stem, root and leaves, were confirmed by specific phytochemical tests. Antimicrobial activity of aqueous and hydroalchoolic fractions were tested against E. coli, S. aureus, P. aeruginosa and C. albicans. The hydroalchoolic fraction revealed antimicrobial activity against all species tested and the aqueous fraction inhibited the growth of S. aureus and C. albicans.Rubus rosaefolius Smith (syn. Rubus rosifolius Smith 7 ) é um arbusto escandente, com poucos acúleos desenvolvidos, frutos isolados, agregados, ocos, rubros na maturidade; cada frutículo drupáceo contém uma semente. As flores axilares e terminais, isoladas, brancas, pentâmeras, com simetria actinomorfa, apresentam cálice gamossépalo e corola dialipétala, com o pedúnculo floral cônico e protuberante, contendo um gineceu apocárpico dialicarpelar. O caule é ramificado, cilíndrico, de cor verde. A raiz primária é pivotante. As folhas são compostas, alternas, imparipenadas, com 3 a 7 folíolos, e estípulas. O limbo dos folíolos é membranáceo, ovado-oblongo, ápice acuminado, base arredondada, áspera ao tato e pubescente à visão. As margens são duplamente denteadas, com nervuras pinadas 8 . O folíolo não apresenta regiões de transparência, à vista desarmada. Acúleos recurvados estão presentes em toda a parte aérea da planta, sendo mais freqüentes nos caules e pecíolos. A espécie floresce o ano todo.

Antioxidant, antimicrobial and anti-quorum sensing activities of Rubus rosaefolius phenolic extract

“…Studies determining the MIC of any type of extract prepared with R. rosaefolius have not been reported. However, Mauro et al (2002) evaluated the antimicrobial acitvity of the aqueous extract obtained from the root, stem and leaves of R. sanguineus which inhibited S. aureus, P. aeruginosa, E. coli and C. albicans. Azevedo,…”

Antimicrobial and Antioxidant Activities of Some Plant Extracts

“…Quercetin isolated from the ethyl acetate extract of A. brasiliana presented antibacterial action against S. aureus (Silva et al, 2011). Antimicrobial activity of aqueous and hydroalchoolic fractions from R. rosifolius leaves showed activity against E. coli, S. aureus, P. aeruginosa and C. albicans (Mauro et al, 2002) and B. trimera was active against S. aureus and E. coli (Avancini et al, 2000). The antifungal activity of the leaf oil of S. chilensis was assayed by paper disk agar diffusion test and showed that human pathogenic dermatophytes were very sensitive (Vila et al, 2002).…”

Chromosome-scale genome, together with transcriptome and metabolome, provides insights into the evolution and anthocyanin biosynthesis of Rubus rosaefolius Sm. (Rosaceae)

“…The mature berry of R. rosaefolius is rich in bioactive ingredients, such as anthocyanins [ 14 ], phenolics [ 15 ], triterpenes, and sterols [ 13 , 16 ]. As a result, it has multiple pharmacological effects, including antioxidant [ 15 ], analgesic [ 17 ], antimicrobial [ 18 ], anticorrosive [ 19 ], antiproliferative [ 13 ], and anticancer effects [16 ], diuresis [ 20 ], and the mitigation of hypertension [ 21 ]. Additionally, the mature berry of R. rosaefolius has a unique sour–sweet taste and is brightly colored, which is attractive.…”