Gênero Pfaffia: aspectos químicos, farmacológicos e implicações para o seu emprego terapêutico

Abstract

Resumo: Os relatos encontrados na literatura científica sobre a composição química e atividades farmacológicas do gênero Pfaffia spp. são apresentados. Os estudos sobre esse gênero são ainda bastante escassos, sendo assim, o uso racional de espécies de Pfaffia, com finalidade terapêutica ainda depende de conhecimento aprofundado de suas propriedades farmacológicas e do desenvolvimento de tecnologias de produção e controle de qualidade.Unitermos: Pfaffia; Panax ginseng; ginseng-brasileiro; fáfia; composição química; atividades farmacológicas.ABSTRACT: Pfaffia: available chemical and pharmacological data and their implications for its therapeutical use. This review summarizes available chemical and pharmacological data about Pfaffia genre. Scientific studies about these species are still lacking, and their therapeutical rational use depends on the availability of more informations about their pharmacological properties and the development of production and control quality technologies.

Anti-inflammatory effects of Brazilian ginseng (Pfaffia paniculata) on TNBS-induced intestinal inflammation: Experimental evidence

“…1). β-Ecdysterone is a marker that allows for the differentiation between P. glomerata and P. paniculata [14,34], and its characterisation is necessary because both Pfaffia species are commercialized as the same product due to the difficulties in their botanical identification [34].…”

“…While the pharmacological effects of other species known as "ginseng" (Eleutherococcus senticosus -Siberian ginseng, Panax quinquefolius -American ginseng, Panax ginsengKorean ginseng, Withania somnifera -Indian ginseng) are widely reported and documented [13], studies on genera Pfaffia and P. paniculata in particular are scarce [11]. This is especially true considering the extent of the use of P. paniculata in Brazil and its importance as an export product to Asian countries [11,14]. …”

Klebsiella pneumoniae Planktonic and Biofilm Reduction by Different Plant Extracts: In Vitro Study

“…Studies indicate that its action potential can be much higher, even against tumor cells in different sites. However, regarding its antimicrobial activity, there is nothing so far described in the literature [9, 10]. …”

Phytochemistry of some Brazilian Plants with Aphrodisiac Activity

“…Although some saponins inhibit PDE-5, like those present in Allium tuberosum, those found in plants studied did not have any reports for this activity (Guohua et al, 2009;Rahimi et al, 2009), except Pfaffia paniculata (Brazilian ginseng) presented saponins as the main active components due to its similarity with those saponins from Panax ginseng, known as ginsenosides (Rates & Gosmann, 2002). The ginsenosides are adaptogens substances or antistress agents, but their action mechanisms are not clear (Schenkel et al, 2007).…”

“…Mimosa tenuiflora (Doyama et al, 2005) Pfaffia paniculata (Amarantaceae) (Rates & Gosmann, 2002) Pharmacological studies of P. paniculata extracts indicate that they might act mainly by increasing central noradrenergic and dopaminergic tone, and possibly (indirectly) oxytocinergic transmission (Arletti et al, 1999).…”