2011
DOI: 10.1590/s0102-36162011000400018
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Ensaios clínicos controlados e randomizados na ortopedia: dificuldades e limitações

Abstract: Randomized controlled clinical trials (RCTs) are considered to be the gold standard for evidence-based medicine nowadays, and are important for directing medical practice through consistent scientific observations. Steps such as patient selection, randomization and blinding are fundamental for conducting a RCT, but some addi-

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Cited by 23 publications
(6 citation statements)
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“…As it is a convenience sample, without a sample calculation, the results of this research based on a non-probabilistic sampling do not allow generalizations regarding the population of interest. The reduced number of subjects may generate a type II error (false negative) which consists in stating that there is no statistical difference in the studied group 39 . As a result of this small sample, it was not possible to do a random allocation with the use of control group.…”
Section: Discussionmentioning
confidence: 99%
“…As it is a convenience sample, without a sample calculation, the results of this research based on a non-probabilistic sampling do not allow generalizations regarding the population of interest. The reduced number of subjects may generate a type II error (false negative) which consists in stating that there is no statistical difference in the studied group 39 . As a result of this small sample, it was not possible to do a random allocation with the use of control group.…”
Section: Discussionmentioning
confidence: 99%
“…almost experimental and non-experimental studies, respectively. This finding may be justified by the difficulty of adapting a methodology to the characteristics of an experimental study [16]. The difficulty of carrying out studies with higher levels of evidence may also justify the publication of more than 75% of papers in scientific journals with Qualis B1 and B2.…”
Section: Discussionmentioning
confidence: 99%
“…Clinical trials aim to create base to support the use of therapies through analysis of different interventions, and these studies have several advantages, especially with regard to the reduction of bias in data collection and analysis, what gives prestige to this method in research [26].…”
Section: Discussionmentioning
confidence: 99%