This article aims to address the issues of Divergence and of distribution of the size of companies in Rio Grande do Sul uaing two methodologies. A comparison of industrial structure between different regions of the state, is made with the index of regional divergence proposed by Krugman (1997). The results show that, despite the trend of reducing disparities in industrial structure, this process is still slow and preserves the existence of strong Divergence. In relation to the size distribution of industries, the various functions of the estimated density indicates a non Gaussian distribution for employment. In addition, the results for the linear model proposed by Zipf (1949) indicate the existence of disparities in opportunity for growth between the sizes of companies. The nonlinear model proposed by Rosen et al. (1980), indicates a concavity function, revealing that the size of intermediary companies, small and medium, representing the dynamics of employment in the sector in the period of analysis.