Chemical profiling of six samples of Brazilian propolis

Fernandes-Silva, Caroline C.; Salatino, Antônio; Salatino, Maria Luiza Faria; Breyer, Ernesto D. H.; Negri, Giuseppina

doi:10.1590/s0100-40422013000200006

Cited by 34 publications

(39 citation statements)

References 20 publications

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“…Nunes et al (2013) stated that the composition of the propolis depends on the season, the vegetation, and the area of collection. Fernandes- Silva et al (2013) also stated that the chemical composition of propolis depends on the plant or plants from which the resin is collected and, consequently, on the geographic location of the hive. According to Franchi et al (2012), the difference in the quality of propolis could be seen from the location and color of a beehive.…”

Section: Introductionmentioning

confidence: 99%

Investigating the antioxidant and anticytotoxic activities of propolis collected from five regions of Indonesia and their abilities to induce apoptosis

Hasan

Mangunwidjaja

Sunarti

et al. 2014

Emir. J. Food Agric

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Propolis is a resinous substance collected by stingless bee or honey bee from various plant sources. The substance is known to contain beneficial properties for human. The geographical origin of propolis determines its biological properties. In this study, propolis were collected from five regions of Indonesia with the objective of determining the yield, their total flavonoid content, their capacity to induce apoptosis, and their toxicity to the Michigan Cancer Foundation-7 (MCF-7) cell line. The inhibition of antioxidant 1,1-diphenyl-2-picrylhydrazyl (DPPH), the induction of apoptosis to Saccharomyces cerevisiae and the anticytotoxic ability were determined. Propolis from Pekanbaru region had higher yield than other regions with value of 19.97%; propolis from Kendal had higher quantity with value of 46.60%, total flavonoid content; propolis from Pandeglang was higher in DPPH oxidation capacity with value of 68.94 μg.ml -1 ; propolis from Kendal, expressed petite cell induction in S. cerevisiae cells with value of 81.44%, and the anticytotoxic to MCF-7 breast cancer cell line were best observed in propolis from Makassar region with a value of 47.71% life cells. All of the propolis extracted from the stingless bee hive Trigona spp from five regions in Indonesia contained flavonoids.

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Section: Introductionmentioning

confidence: 99%

Investigating the antioxidant and anticytotoxic activities of propolis collected from five regions of Indonesia and their abilities to induce apoptosis

Hasan

Mangunwidjaja

Sunarti

et al. 2014

Emir. J. Food Agric

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“…27 Coumarins were identified in the 28 propolis samples among studied 64 ones. Similarly, Fernandes-Silva et al [18] found flavanoids as major constituents of the samples from Minas Gerais, Brazil. Pinostrobin chalcone and pinocembrin were determined in most of the propolis samples.…”

Section: Resultsmentioning

confidence: 78%

Chemical Characterization of 64 Propolis Samples from Hakkari, Turkey

Bayram¹,

Sorkun²,

Öz³

et al. 2018

Rec.Nat.Prod.

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Propolis is a resinous substance produced by honey bees from various plants they visit. Sixty-four propolis samples were collected from different localities of four districts (Merkez, Yüksekova, Şemdinli, and Çukurca) in Hakkari territory. Ethanol extracts of the propolis samples were prepared, and their chemical contents were determined by gas chromatography-mass spectroscopy (GC-MS). Flavonoids were generally found in a high concentration in Şemdinli samples of Turkey. Twenty-seven coumarins were identified in the 28 propolis samples among studied 64 ones. Except suberosin, the coumarins were never reported before in any propolis sample with Turkish origin. The propolis samples belonging to Yüksekova were found to be richer in coumarins than the others, and the most richest one among the Yüksekova apiaries, was found to be Akocak sample (Y2) with 41.99% total yield, followed by Akçalı sample (Y5) (30.86%). This is a first comprehensive and original report about the chemical profile of propolis samples from Hakkari. The propolis samples from Hakkari exhibited a chemical content rich in flavonoids including coumarins and furocoumarins.

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“…The methanol extract and all fractions were concentrated under reduced pressure and dissolved in ethanol for analysis. Chemical composition of the six samples are published elsewhere [8]. …”

Section: Methodsmentioning

confidence: 99%

“…Results of analyses by GC/MS and HPLC/DAD/ESI/MS/MS of four samples of propolis from the state of Minas Gerais (MG, Southeast Brazil) and two from the state of Paraná (PR, South Brazil) were published recently [8]. The samples from the two states differed regarding the exclusive presence of luteolin-5- O -methyl ether in the samples from Paraná, a region on the border of the distribution of Baccharis dracunculifolia .…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic Activity of Six Samples of Brazilian Propolis on Sea Urchin (Lytechinus variegatus) Eggs

Fernandes-Silva

Freitas

Salatino

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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The cytotoxic activities of extracts of four samples of propolis from the state of Minas Gerais (Southeast Brazil) and two from the state of Paraná (South Brazil) were evaluated using sea urchin (Lytechinus variegatus) eggs. Cytotoxic activity was observed, characterized mainly by the inhibition of the first cleavage of newly fertilized eggs. Methanol extracts at 32 µg mL−1 of all samples were highly active (97–100%). Extracts were also prepared by successive treatments of the samples with hexane, chloroform, ethyl acetate, and methanol. High activity was observed using the ethyl acetate fractions of all samples, but hexane and chloroform fractions of some samples also had high activity. Based on the chemical composition of the extracts and fractions (published previously), it is hypothesized that the cytotoxic activities observed are due mainly to artepillin C, p-coumaric acid, and kaempferide. The results suggest that caffeoylquinic acids have no cytotoxic activity in sea urchin eggs.

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Chemical profiling of six samples of Brazilian propolis

Cited by 34 publications

References 20 publications

Investigating the antioxidant and anticytotoxic activities of propolis collected from five regions of Indonesia and their abilities to induce apoptosis

Investigating the antioxidant and anticytotoxic activities of propolis collected from five regions of Indonesia and their abilities to induce apoptosis

Chemical Characterization of 64 Propolis Samples from Hakkari, Turkey

Cytotoxic Activity of Six Samples of Brazilian Propolis on Sea Urchin (Lytechinus variegatus) Eggs

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