“…Thus, it 5, 9, 13, 20, 22, 25, 28 a 0.857 0.906 0.849 3, 5, 9, 14, 20, 21, 25 0.869 0.916 0.844 2, 5, 7, 14, 18, 26, 32 0.828 0.898 0.893 3, 7, 9, 14, 17, 27, 31 0.855 0.906 0.857 1, 3, 6, 11, 19, 23, 31 0.863 0.898 0.905 32, 10, 15, 20, 2, 28, 6 0.864 0.904 0.816 4, 5, 10, 16, 18, 22, 27 0.823 0.890 0.906 3, 8, 9, 11, 17, 21, 24 0.828 0.880 0.909 1, 3, 5, 7, 9, 11, 13 can provide information about the tridimensional coordinates of atoms (Strandsls, 2007). These descriptors are directly related to the form and volume occupied by a molecule, where higher values can represent the total occupation of the binding site on biological target (Freitas et al, 2009). The regression vector to indicates that higher values for this descriptor increase the activity.…”