2011
DOI: 10.1590/s0080-62342011000100005
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Avaliação do diagnóstico da sepse neonatal: uso de parâmetros laboratoriais e clínicos como fatores diagnósticos

Abstract: The purpose of this study was to describe and compare the clinical, laboratory and health care characteristics of newborns (NBs) with confirmed late onset sepsis and NBs with unconfirmed late sepsis, verify if there were any differences between the groups, and describe the germs prevalent in the studied neonatal unit. This is a descriptive study, involving 168 cases. It was observer that 33.3% had a confirmed diagnosis for late onset sepsis. The age at the time of sepsis onset, the length of stay, the total nu… Show more

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Cited by 17 publications
(17 citation statements)
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“…(10,22,25) The study by Nambiar et al demonstrates a higher prevalence of Gram-negative bacteria (43%), predominantly Enterobacter spp. (26) A high proportion of Klebsiella pneumoniae among isolated Gram-negative bacteria was also documented by Tragante et al and Meireles et al (4,21) However, some studies have reported a predominance of Gram-positive bacteria, including coagulase-negative Staphylococcus. Among cultured Gram-negative bacteria, Pseudomonas spp.…”
Section: Discussionmentioning
confidence: 80%
See 1 more Smart Citation
“…(10,22,25) The study by Nambiar et al demonstrates a higher prevalence of Gram-negative bacteria (43%), predominantly Enterobacter spp. (26) A high proportion of Klebsiella pneumoniae among isolated Gram-negative bacteria was also documented by Tragante et al and Meireles et al (4,21) However, some studies have reported a predominance of Gram-positive bacteria, including coagulase-negative Staphylococcus. Among cultured Gram-negative bacteria, Pseudomonas spp.…”
Section: Discussionmentioning
confidence: 80%
“…(2)(3)(4)(5)(6) However, the proportion of positive blood cultures among the patients with sepsis (17.1%) was lower than the figures reported in the literature (18% to 65%). (6,7,20,21) The blood cultures from the three patients who died revealed Gram-negative bacteria, raising the possibility that these agents are associated with increased mortality. This finding agrees with CohenWolkowiez et al and Gordon et al, who found that increased mortality ranging from 19% to 24% was related to Gram-negative bacteria.…”
Section: Discussionmentioning
confidence: 99%
“…Ademais, uma investigação realizada na Ásia identificou que há associação entre o diagnóstico da sepse neonatal com a presença da hemocultura positiva, baixo peso ao nascer e prematuridade (14)(15) . Assim, é possível inferir que a prematuridade associada ao baixo peso ao nascer constituem fatores de risco importantíssimos para o desenvolvimento da sepse (12,(16)(17) .…”
Section: Condições De Nascimento E Prematuridadeunclassified
“…isoladas nas hemoculturas, observou-se a prevalência de K. pneumoniae, S. aureus, além da presença marcante de S. coagulase negativa (12) .…”
Section: Os Fatores De Risco Observados No Estudo Equivalem Aos Enconunclassified