Predictors of favorable results in pulmonary tuberculosis treatment (Recife, Pernambuco, Brazil, 2001-2004)

Sassaki, Cinthia Midori; Scatena, Lúcia Marina; Gonzáles, Roxana Isabel Cardozo; Ruffino-Netto, Antônio; Hino, Paula; Villa, Tereza Cristina Scatena

doi:10.1590/s0080-62342010000200037

Cited by 8 publications

(8 citation statements)

References 8 publications

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“…As reported in the national 11 and international 12 literature, in Rondônia there was a predominance of cases in males, however, the sex ratio (male/female) among the indigenous peoples (1.3/1) was lower to what is usually described in the general population in the country, which is around 1.7/1 (www.datasus.gov.br).…”

Section: Discussionmentioning

confidence: 84%

Características sociodemográficas e indicadores operacionais de controle da tuberculose entre indígenas e não indígenas de Rondônia, Amazônia Ocidental, Brasil

Orellana

Gonçalves

Basta

2012

Rev. bras. epidemiol.

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With the intention of improve knowledge on the epidemiological situation of tuberculosis (TB) among vulnerable populations in Brazil, our objective was to analyze sociodemographic characteristics and operational indicators related to TB control, comparing indigenous and non-indigenous people, in Rondônia. We conducted a retrospective and descriptive epidemiological study of new TB cases reported between 1997, January 1st and 2006, December 31st. We excluded duplicate records and those for whom the results of treatment was change in diagnosis and transfer. TB cases were classified into two categories: indigenous and non-indigenous people and analysis was performed according to sex, age, origin (urban /rural), State of residence, clinical form, diagnostic tests, monitoring indicators and results of treatment. Altogether 4832 cases were reported, with 322 cases (6.7%) in indigenous people. There was a male predominance (ratios: 1.7 to 1.3 in non-indigenous and indigenous people). The majority of cases for indigenous people (82.6%) was in rural area and there was high concentration of cases (36.0%) in children < 15 years. The analysis of diagnostic tests showed a predominance of smear positive in non-indigenous (56.1%) and smear negative and smear not performed in indigenous people (31.7% and 35.4% respectively, P value=0.0001). There was difference in the monitoring in relation to smear of second month (6.1% positivity, P value = 0.0001) and exam at least one contact (69.6%, P value = 0.017) for non-indigenous. On the other hand, DOTS was more associated with indigenous people cases (23.6%, P value = 0.0001). Stands out the predominance of cure in both groups, with bigger concentration in indigenous people (90.4%, P value = 0.0001) and higher rate of noncompliance in non-indigenous (14.7%, P value = 0.0001). The approach showed useful for elucidate inequalities and has exceeded the usual analysis carried out surveillance on services that aim to delineate the epidemiological situation based only on rates or absolute values.

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Section: Discussionmentioning

confidence: 84%

Características sociodemográficas e indicadores operacionais de controle da tuberculose entre indígenas e não indígenas de Rondônia, Amazônia Ocidental, Brasil

Orellana

Gonçalves

Basta

2012

Rev. bras. epidemiol.

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“…[ 23 ] In a study carried out in Brazil, it was shown that pulmonary TB patients under the age of 20 years had a better chance of recovery than patients older than 60 years. [ 33 ] Results of studies Sterling et al . [ 34 ] and Yen et al .…”

Section: Discussionmentioning

confidence: 99%

“…The Brazilian study showed that new and relapsed patients had a greater chance of recovery than patients who had treatment again after failure. [ 33 ]…”

Section: Discussionmentioning

confidence: 99%

Factors affecting mortality and treatment completion of tuberculosis patients in Isfahan Province from 2006 to 2011

2015

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Background:Regarding cases of infectious diseases tuberculosis (TB) is the most important cause of death and according to the DALY criteria, this disease has the seventh position in global disease ranking. In this study, we aim to determine the risk factors, which have a significant effect on the treatment completion and mortality of TB patients.Methods:This study is a retrospective cohort study. The sample is made up of registered TB patients in the Isfahan Province from 2006 to 2011. Information of the patients was collected from their files in health centers in the Isfahan Province. Variables such as age, sex, weight, nationality, residence, type of TB, imprisonment, human immunodeficiency virus, TB case were measured. Descriptive statistics (including frequency, percentage, mean and standard deviation) and statistical analysis (including Cox proportional hazard model) were used.Results:The result showed that imprisonment (hazard ratio [HR] = 4.76, P = 0.019), age (HR = 4.44, P = 0.001) and the TB case (HR = 2.73, P = 0.037) of pulmonary TB had significant impacts on mortality of the patients, also in the case of treatment completion, the TB case (HR = 0.34, P < 0.001) proved to have a significant impact on completion of the treatment. Type of extra-pulmonary TB in extra-pulmonary TB patients also had an effect on treatment completion.Conclusions:We can conclude that factors such as age, imprisonment, TB case and type of extra-pulmonary TB are effective on the treatment completion and mortality of the patients. It may be useful for policy makers to make more control of high-risk patients.

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“…Studies have shown that individual characteristics such as advanced age, being male, history of TB treatment, alcohol abuse, and mixed or extrapulmonary clinical presentation, as well as the presence of diabetes, HIV, cancer, or other respiratory diseases, may contribute to risk of death from TB. Social conditions such as low educational level and poverty also contribute to poor outcomes (7–9).…”

mentioning

confidence: 99%

Effect of inpatient and outpatient care on treatment outcome in tuberculosis: a cohort study

Rocha

Oliveira

Saraceni

et al. 2018

Rev Panam Salud Publica

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Objective To identify individual- and health services–related factors associated with deaths in subjects diagnosed with tuberculosis (TB). Methods A nonconcurrent cohort study with passive follow-up was conducted using a probabilistic linkage method to analyze a sample of patients diagnosed and reported as having TB in 2006 and followed up until 2008. New cases, cases with previous treatment (readmission after loss to follow-up or relapse), and transfers across health services were included. Proportional hazards models were used to estimate the independent effect of covariates related to the individual and to the health services on mortality from all causes. Results Age above 60 years, admission to a hospital with emergency services, HIV-associated TB, and readmission to an outpatient facility after disease relapse or loss to follow-up were identified as risk factors for death. Variables related to process and results indicators of Brazil's National TB Program were not associated with mortality from all causes. Conclusions Advanced age, previous treatment for TB, and treatment at a secondary-level outpatient facility or a hospital with emergency services on site were associated with mortality in TB patients. Better strategies to improve TB care delivered at health units are needed to prevent death from TB, especially among the elderly.

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Predictors of favorable results in pulmonary tuberculosis treatment (Recife, Pernambuco, Brazil, 2001-2004)

Cited by 8 publications

References 8 publications

Características sociodemográficas e indicadores operacionais de controle da tuberculose entre indígenas e não indígenas de Rondônia, Amazônia Ocidental, Brasil

Características sociodemográficas e indicadores operacionais de controle da tuberculose entre indígenas e não indígenas de Rondônia, Amazônia Ocidental, Brasil

Factors affecting mortality and treatment completion of tuberculosis patients in Isfahan Province from 2006 to 2011

Effect of inpatient and outpatient care on treatment outcome in tuberculosis: a cohort study

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