Abandono do tratamento de tuberculose em co-infectados TB/HIV

Abstract

This study aimed at analyzing the reasons that patients co-infected with tuberculosis and HIV leave the treatment of tuberculosis and to know the conduct of the health team toward that abandonment. The study, using a qualitative approach, performed semi-structured interviews on 45 professionals working at a referral health center in Pará state. Two units emerged based on the thematic analysis: patient-associated factors that make TB treatment adherence difficult; and service-associated factors that contribute to treatment abandonment. It was found that, in terms of the patients, that their low socioeconomic condition was the most common factor that led to abandonment. Other factors that led to this outcome included the adverse drug effects, the use of illegal drugs, and poor personal motivation. Regarding the service, issues related to the physical structure, working process organization and accessibility were also relevant to their non-adherence. Results show there is a need to change the practices performed at the health care services.

Factors associated with tuberculosis by HIV status in the Brazilian national surveillance system: a cross sectional study

“…Patients with TB require long-term treatment with various medications. For patients with TB-AIDS, adherence with the treatment regimen is difficult due to the extra burden of drug taking, resulting in higher default rate as showed in our study [26–28]. Because of this difficulty and poor adherence to tuberculosis treatment, new strategies for monitoring treatment should be devised, taking into account the characteristics of the co-infection as recommended by Brazilian National Tuberculosis Control.…”

Improving tuberculosis control through the partnership between university and the health system

“…Factors related to non-compliance with anti-TB treatment may be of a different nature and have been linked, among others, to the use of alcohol and other drugs [23][24][25] . A study conducted between 1995 and 1996 in the same city showed that 20% of patients diagnosed in a year abandoned the anti-TB treatment; 24.2% of these patients were alcohol users 26 .…”

Associação entre tuberculose e uso de drogas psicotrópicas em pacientes internados num hospital público de referência na cidade de Salvador/BA

“…O Brasil é o décimo oitavo colocado no ranking dos países com maior índice de TB no mundo [2], com ocorrência de 4.5 mil mortes por ano [3]. As maiores incidências da TB estão nos estados do Rio de Janeiro (73,27 por 100 mil/ hab.…”

“…E em Salvador a taxa de incidência é de 79,35/100 mil habitantes. Nos últimos anos, o maior impacto negativo no controle da TB foi observado nas grandes cidades, em virtude da piora das condições socioeconômicas locais [2].…”