Prevalência e correlatos de doença vascular no exame de ultrassom em pacientes em hemodiálise

Abstract

Background: Patients on hemodialysis present an increased risk of cardiovascular death. Intimal media thickness (IMT) and presence of arterial calcifications are well-known risk factors for cardiovascular death in hemodialysis patients.

Effect of VDRA on survival in incident hemodialysis patients: results of the FARO-2 observational study

“…The small sample size also precluded the possibility of evaluating the possibility of any potential dose-related effect of VDRA therapy on overall survival. In addition, although some classical factors did not attain statistical significance, possibly again attributed to the low sample number, several other clinical characteristics emerged as risk factors for survival, corroborating other studies [ 32 , 40 , 41 ]. Furthermore it was retrospective and observational design.…”

“…In fact, as previously observed in the FARO study, [ 32 ] in the present analysis we have also noted that the presence of vascular disease was a significant predictor of mortality. In line with these data, vascular-related comorbidities have previously been linked to increased morbidity and mortality in HD patients [ 40 , 41 ]. There is no clear explanation on the precise mechanisms by which VDRA therapy might provide its cardio-vascular protective effects.…”

Survival and Predictive Factors of Lethality in Hemodyalisis: D/I Polymorphism of The Angiotensin I-Converting Enzyme and of the Angiotensinogen M235T Genes

“…The prevalence of arterial hypertension in our study (82%) was higher than the Bahia study (71%) 9 , and higher than the analysis of six hemodialysis clinics in the State of Rio de Janeiro (61%) 10 ; it was also higher than the single center study conducted in the State of Rio de Janeiro (55%) 11 .…”

“…Diabetes mellitus prevalence in this study (15%) was much lower than that found in the 2010 Census by the Brazilian Society of Nephrology (28%) 4 , lower than the Bahia study (21%) 9 , and lower than the single center study in the State of Rio de Janeiro (20%) 11 . However, it was similar to the analysis involving six hemodialysis clinics in the State of Rio de Janeiro (17%) 10 .…”

“…The mean age of the study population was 46 years, which is lower than that found in a study in the State of Rio de Janeiro 10 (54 years old), and also lower than another cross-sectional analysis conducted in a single dialysis center in the State of Rio de Janeiro, where the mean age was 52 years 11 . However, it was similar to the Bahia study 9 , which found a mean age of 49 years.…”