Suscetibilidade antimicrobiana in vitro dos Staphylococcus coagulase negativa oculares

Gayoso, Maria de Fátima; Oliveira, Adália Dias Dourado; d’Azevedo, Pedro Alves; Yu, Maria Cecília Zorat; Höfling-Lima, Ana Luísa; Francisco, Waldemar

doi:10.1590/s0004-27492007000600007

Cited by 7 publications

(2 citation statements)

References 16 publications

(15 reference statements)

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“…Because of their ubiquitous nature and relatively low virulence, staphylococci, other than S. aureus, in the past were often simply reported by the microbiology laboratory as CoNS. However, over the past 15 years, there has been increased documentation of ocular infections caused by CoNS (1,(5)(6)9,(25)(26) . Because the antimicrobial susceptibility of CoNS is unpredictable, and because multiresistant isolates are common, the recommendation now is to perform antimicrobial susceptibility testing in all cases of clinically significant ocular infections caused by these organisms.…”

Section: Discussionmentioning

confidence: 99%

“…Resistance to methicillin is associated with in vitro crossing resistance to other antimicrobials (6,8) . The laboratory data from the Ophthalmological Department of the University of São Paulo (UNIFESP) has documented a recent increase in infections due to this microorganism (9) . In contrast to infection at other sites, the ocular therapeutic difficulties posed by the MRCoNS have been virtually unrecognized.…”

Section: Introductionmentioning

confidence: 99%

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Laboratory detection methods for methicillin resistance in coagulase negative Staphylococcus isolated from ophthalmic infections

Oliveira¹,

d’Azevedo²,

Sousa³

et al. 2007

Arq. Bras. Oftalmol.

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In the present study, we found that the E-test and the oxacillin salt agar screening test S (0.75 microg oxacillin per ml), when compared with polymerase chain reaction, were the most accurate currently available methods to phenotypically detect oxacillin resistance of coagulase negative Staphylococcus species. This study demonstrated that a good option for screening of ocular isolates for oxacillin resistance in the microbiology laboratory is the cefoxitin disk diffusion test and the automated Vitek system. We believe it is important to have available methods that accurately detect methicillin resistance of the less commonly encountered species, chiefly because of their increasing importance as opportunistic pathogens.

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