Análisis bacteriológicos en el tratamiento de las conjuntivitis. Comparación de la resistencia a antibióticos entre 1982 y 2008

Carreras, B. A.

doi:10.1016/j.oftal.2011.11.017

Cited by 3 publications

(2 citation statements)

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“…However, the pathogens of some bacterial endophthalmitis, bacterial corneal ulcers, blepharitis, conjunctivitis, and other ocular infection diseases turned out to consistent with conjunctival isolated bacteria, and the S. epidermidis has become the predisposing pathogen (Recchia et al, 2005; Carreras, 2012; Sharma et al, 2013). Although, the preoperational topical antibiotics can hardly make the conjunctival sacs sterile, they can effectively reduce the isolating bacteria (Mshangila et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…Although, the preoperational topical antibiotics can hardly make the conjunctival sacs sterile, they can effectively reduce the isolating bacteria (Mshangila et al, 2013). The susceptibility of each antibiotic to different bacteria is not identical, and the regional reported drug resistance varies widely due to different environment and the use of antibiotics (Carreras, 2012; Mshangila et al, 2013; Muluye et al, 2014). The overall incidence of isolated bacteria was 24.2%, and we found higher resistance rates to penicillic, macrolides, clindamycin and sulfonamides by CONS, ranging from 57.9 to 90.8%.…”

Section: Discussionmentioning

confidence: 99%

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Incidence and Antimicrobial Sensitivity Profiles of Normal Conjunctiva Bacterial Flora in the Central Area of China: A Hospital-Based Study

Tao

Wang

et al. 2017

Front. Physiol.

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Objective: To study the distribution and patterns of resistance to antimicrobial agents of normal conjunctival bacteria. Materials and Methods:Conjunctival specimens were collected from 8,224 patients and then cultured, which underwent antimicrobial susceptibility test following standard methods. Patients with infectious symptoms such as erythema or oedema and those using systemic or topical antibiotics within 1 month were excluded.Results: In this study, the incidence of isolated bacteria was 24.2%. The middle aged group of 41-65 years presented the lowest rate of bacterial isolation which was 19.4%, while the highest isolation rate (83.1%) was found in patients in the age range of 0-6 years. In every age group, the incidence of bacterial isolation in men was higher than that in women. The top 3 most commonly isolated micro-organisms were Staphylococcus epidermidis (39.7%), Streptococcus pneumoniae (4.5%), and Staphylococcus aureus (2.7%), of which about 83.1% S. aureus were isolated in the group of 0-6 years. We found that coagulase-negative Staphylococcus (CONS) were more resistant to penicillin, macrolides, clindamycin and sulfonamides with the rate ranging from 57.9 to 90.8%, which were highly susceptible to vancomycin, linezolid, rifampin, tetracyclines, and aminoglycosides. Contrasting to CONS, the general resistance rate of S. aureus was significantly lower. Additionally, Streptococcus was susceptible well to the majority of antimicrobial agents, while highly resistant to macrolides and tetracyclines with the rate >80%. Conclusions:In conclusion, our study revealed the incidence and antimicrobial sensitivity profiles of normal conjunctiva bacterial flora in the central area of China, which could be useful in the prevention of ocular infections. Importantly, our data could be used to guide the selection of appropriate prophylactic agents.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Incidence and Antimicrobial Sensitivity Profiles of Normal Conjunctiva Bacterial Flora in the Central Area of China: A Hospital-Based Study

Tao

Wang

et al. 2017

Front. Physiol.

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Besifloxacin in the management of bacterial infections of the ocular surface

Deschênes

Blondeau

2015

Canadian Journal of Ophthalmology

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Bacterial etiology and antimicrobial resistance trends in ocular infections: A 30-year study, Turin area, Italy

Grandi

Bianco

Boattini

et al. 2019

European Journal of Ophthalmology

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Purpose: Bacterial ocular infections can result in loss of all or part of the ocular structures, contributing to a high disability charge. Local surveillance of etiology and susceptibility patterns is crucial for an appropriate empiric management of ocular infections. The aim of this study was to analyze of bacterial spectrum in culture-proven ocular infections and trends of antimicrobial susceptibility patterns. Methods: A monocentric retrospective study was performed including ocular infection cases diagnosed at the Microbiology Unit of Turin Ophthalmic Hospital between 1988 and 2017. Spectrum of pathogens that caused bacterial culture-proven ocular infections and trends of antimicrobial susceptibility patterns were analyzed. Results: A total of 15,517 culture-positive isolates were identified as causative agents of ocular infections. Gram-positive bacteria were deemed to cause infection in 73.5% of cases. Staphylococcus spp. and Pseudomonas spp., coagulase-negative staphylococci, Staphylococcus aureus were the leading causative pathogens of keratitis, endophthalmitis, and conjunctivitis, respectively. Statistically significant changes in temporal trends were observed for all analyzed microorganism groups except for Enterobacteriaceae group. Overall, fluoroquinolones and chloramphenicol demonstrated to be the most effective antimicrobials in vitro toward bacterial ocular infections, followed by tetracycline, ampicillin, and aminoglycosides. Enterobacteriaceae isolates showed higher multi-drug resistance rate, followed by coagulase-negative staphylococci. Analysis of resistance rates over time highlighted increasing resistance trend for aminoglycosides among Gram-negative and for both aminoglycosides and fluoroquinolones among Gram-positive pathogens, especially for S. aureus. Conclusion: This study provided a 30-year assessment of bacterial ocular infections in an urban area of Italy, giving support to epidemiological consciousness and guiding empiric antimicrobial therapy.

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Análisis bacteriológicos en el tratamiento de las conjuntivitis. Comparación de la resistencia a antibióticos entre 1982 y 2008

Cited by 3 publications

References 13 publications

Incidence and Antimicrobial Sensitivity Profiles of Normal Conjunctiva Bacterial Flora in the Central Area of China: A Hospital-Based Study

Incidence and Antimicrobial Sensitivity Profiles of Normal Conjunctiva Bacterial Flora in the Central Area of China: A Hospital-Based Study

Besifloxacin in the management of bacterial infections of the ocular surface

Bacterial etiology and antimicrobial resistance trends in ocular infections: A 30-year study, Turin area, Italy

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